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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
1,988,827 |
125,597 |
| US |
606,242 |
25,394 |
Research News
PUBLISHED: Virus becomes undetectable before infection is over in some patients, frontline docs create better triage algorithms, and SARS-CoV2 reproduces far more rapidly than SARS-CoV. UNPUBLISHED: Daily screening of population samples may control outbreaks moving forward, transmission on Diamond Princess primarily through personal contact and fomites, and reducing Health Service spending associated with increased COVID-19 case-fatality-rate.
PEER REVIEWED
- A paper mentioned in a previous newsletter looking at positive PCR testing after repeat 24 hour negative tests suggests that levels of the virus may oscillate, particularly for those with less severe symptoms. This should not be taken to mean that the infection entirely disappeared and then re-emerged as some media reports have suggested.
- Triage protocols for Covid-19 developed independently by staff in a Singapore Emergency Room were far more sensitive and specific than those recommended by the national public health service.
- A comparison of SARS-CoV and SARS-CoV-2 shows that the new virus grows far more rapidly in cell culture but produced a far weaker immune response, not triggering interferon at all and activating only 5 of 13 pro-inflammatory mediators.
MANUSCRIPTS- NOT PEER REVIEWED
- A model developed by Swiss physicists demonstrates the critical importance of active surveillance in controlling outbreaks as lockdowns end.
- An analysis of the Diamond Princess Cruise ship suggests that the primary mode of spread for Covid-19 was through close personal contact and fomites and not through long distance airborne transmission.
- An analysis of national case fatality rates suggests that, within the OECD, those countries which have reduced health service expenditures tended to experience higher rates of negative outcomes for Covid-19 patients.
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- Covid19- Ahead of the Curve.
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Top News
- Using random testing to manage a safe exit from the COVID-19 lockdown MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Transmission routes of Covid-19 virus in the Diamond Princess Cruise ship MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
- PCR Assays Turned Positive in 25 Discharged COVID-19 Patients Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
- Estimating Impact of Austerity policies in COVID-19 fatality rates:Examining the dynamics of economic policy and Case Fatality Rates (CFR) of COVID-19 in OECD countries MedRxiv Server for Health Sciences: Coronavirus, April 13, 2020
- Containing COVID‐19 in the emergency room: the role of improved case detection and segregation of suspect cases Wiley: Coronavirus Research & News, April 13, 2020
Virology, Immunology, and Pathophysiology
- Good IgA bad IgG in SARS-CoV-2 infection? Oxford Academic Journals: Coronavirus, April 13, 2020
- Distinct characteristics of COVID‐19 patients with initial rRT‐PCR positive and negative results for SARS‐CoV‐2 Wiley: Coronavirus Research & News, April 13, 2020
- Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic. NIH: National Library of Medicine: Coronavirus, April 14, 2020
Infection Control
- Nonpharmaceutical interventions and epidemic intensity during the 2019 novel coronavirus disease pandemic Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
- COVID‐19 indirect contact transmission through the oral mucosa must not be ignored Wiley: Coronavirus Research & News, April 13, 2020
- Factors associated with prolonged viral RNA shedding in patients with COVID-19 Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
Clinical
- Efficacy of remdesivir versus placebo for the treatment of COVID-19: A protocol for systematic review and meta-analysis of randomized controlled trials MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Analysis of factors associated early diagnosis in coronavirus disease 2019 (COVID-19) MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Predictors of refractory Coronavirus disease (COVID-19) pneumonia Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
Epidemiology
- Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19). NIH: National Library of Medicine: Coronavirus, April 14, 2020
- Relationship between Average Daily Temperature and Average Cumulative Daily Rate of Confirmed Cases of COVID-19 MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Influenza‐like illnesses caused by a cluster of imported Italian COVID‐19 Wiley: Coronavirus Research & News, April 13, 2020
- Lockdown contained the spread of 2019 novel coronavirus disease in Huangshi city, China: Early epidemiological findings Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
- Cluster of coronavirus disease 2019 (Covid-19) in the French Alps, 2020 Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
Modeling and Prediction
- Forecasting Covid-19 Outbreak Progression in Italian Regions: A model based on neural network training from Chinese data MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- COVID-19 in India: Predictions, Reproduction Number and Public Health Preparedness MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Tracing DAY-ZERO and Forecasting the Fade out of the COVID-19 Outbreak in Lombardy, Italy: A Compartmental Modelling and Numerical Optimization Approach. MedRxiv Server for Health Sciences: Coronavirus, April 13, 2020
- Method for Active Pandemic Curve Management (MAPCM) MedRxiv Server for Health Sciences: Coronavirus, April 13, 2020
- Diminishing Marginal Benefit of Social Distancing in Balancing COVID-19 Medical Demand-to-Supply MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
Review and Commentary
- Public health concerns and unsubstantiated claims at the intersection of vaping and COVID-19 Oxford Academic Journals: Coronavirus, April 14, 2020
- My Future in Medicine: How COVID-19 is Inspiring the Next Generation of Infectious Disease Specialists Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
- Near- and forecasting the SARS-COV-2 epidemic requires a global view and multiple methods MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
Mental Health
- Mental Health and the Covid-19 Pandemic New England Journal of Medicine: Coronavirus, April 13, 2020
- Care for the psychological status of frontline medical staff fighting against COVID-19 Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
- “We’re staying at home”. Association of self-perceptions of aging, personal and family resources and loneliness with psychological distress during the lock-down period of COVID-19 Oxford Academic Journals: Coronavirus, April 13, 2020
- Preventing Suicide in Rural Communities During the COVID‐19 Pandemic Wiley: Coronavirus Research & News, April 13, 2020
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Coronavirus Research Resources
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China
- Forecasting Covid-19 Outbreak Progression in Italian Regions: A model based on neural network training from Chinese data MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Lockdown contained the spread of 2019 novel coronavirus disease in Huangshi city, China: Early epidemiological findings Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
- China's Heilongjiang Reports 79 New Imported Coronavirus Cases: CCTV New York Times: Coronavirus, April 13, 2020
- Five-step plan for reopening business is put to the test in China Washington Post: Coronavirus, April 13, 2020
South Korea
- TOKYO (AP) — South Korean officials warned Monday that hard-earned progress fighting the coronavirus pandemic could be upset by new infections at bars and leisure spots, highlighting global... AP Health News: Coronavirus, April 13, 2020
- The Latest: South Korea vice health minister urges alertness AP Health News: Coronavirus, April 13, 2020
- Kia Motors Considers Halting Three South Korean Plants as Virus Hits Exports New York Times: Coronavirus, April 12, 2020
Italy
- Forecasting Covid-19 Outbreak Progression in Italian Regions: A model based on neural network training from Chinese data MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Italian Physical Therapists’ Response to the Novel COVID-19 Emergency Oxford Academic Journals: Coronavirus, April 13, 2020
- Tracing DAY-ZERO and Forecasting the Fade out of the COVID-19 Outbreak in Lombardy, Italy: A Compartmental Modelling and Numerical Optimization Approach. MedRxiv Server for Health Sciences: Coronavirus, April 13, 2020
- Italian Physical Therapists’ Response to the Novel COVID-19 Emergency Oxford Academic Journals: Coronavirus, April 12, 2020
Spain
- Hard-Hit Spain Tries A Gradual Easing Of Its Coronavirus Lockdown NPR: Health, April 13, 2020
Germany
- Where Germany had success in fighting coronavirus, Britain stumbled Washington Post: Coronavirus, April 13, 2020
France
- Cluster of coronavirus disease 2019 (Covid-19) in the French Alps, 2020 Infectious Diseases Society of America Journals: Coronavirus, April 13, 2020
United Kingdom
- Where Germany had success in fighting coronavirus, Britain stumbled Washington Post: Coronavirus, April 13, 2020
Other International News
- COVID-19 in India: Predictions, Reproduction Number and Public Health Preparedness MedRxiv Server for Health Sciences: Coronavirus, April 14, 2020
- Putin Warns That Russia's COVID-19 Pandemic Is Getting Worse NPR: Health, April 14, 2020
- Russia's coronavirus cases expected to soar ABCNews: Top Coronavirus Stories, April 13, 2020
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Business and Economic News
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Business News
- Covid-19 numbers show promise, but health experts warn each state is a different battleground CNN.com - Health, April 14, 2020
- Photos show bodies piled up and stored in vacant rooms at Detroit hospital CNN.com - Health, April 14, 2020
- Heart risk concerns mount around use of chloroquine and hydroxychloroquine for Covid-19 treatment CNN.com - Health, April 14, 2020
Economics Blogs
- COVID-19 day care centre closures and parental time use VoxEU.org, April 14, 2020
- Measuring the impact of the German public shutdown on the spread of COVID-19 VoxEU.org, April 14, 2020
- Coronavirus dashboard for April 13: Plateauing and stasis Angry Bear, April 14, 2020
Top Economics News
- Latest on the spread of the coronavirus around the world - WTVB News (Brazilian Economy), April 14, 2020
- A Brazilian industry COVID-19 hasn't stopped: deforestation in the Amazon - MercoPress (Brazilian Economy), April 14, 2020
- Tuesday, April 14: Coronavirus global update - Cyprus Mail (Brazilian Economy), April 14, 2020
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Law Technology
- How Twitter can help track the spread of COVID-19 RealKM, April 14, 2020
- COVID-19: Making sense of information in a global pandemic Vable Blog, April 14, 2020
- LawNext Episode 71: Legal Futurist Richard Susskind on Coronavirus, Courts and the Legal Profession Robert Ambrogi's LawSites, April 13, 2020
Legal Administrator
- Helping Employees Stay Well During COVID-19 EntertainHR, April 14, 2020
- LawNext Episode 71: Legal Futurist Richard Susskind on Coronavirus, Courts and the Legal Profession Law Sites Blog, April 13, 2020
- U.S. Department of Labor Issues Alert to Keep Package Delivery Workers Safe During COVID-19 Pandemic OSHA News Releases, April 13, 2020
Librarian News
- Coronavirus in Chicago Jail: Sarah Grady, Lawyer House of Butter, April 14, 2020
- USA: Coronavirus Refunds & Cancellations: How to Get One (LegalEagle’s Real Law Review) House of Butter, April 14, 2020
- PODCAST: JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH: COVID-19 and the Law House of Butter, April 14, 2020
Leading Law Departments
- Law Firm Updates: COVID-19’s Impact on the Business of Law Legal Executive Institute: Blog, April 13, 2020
- Of Lions and Lambs in the Time of Coronavirus Inside Counsel, April 13, 2020
- COVID-19 and the Rated Order: Must You Change Manufacturing Locations, Sources for PPE? Inside Counsel, April 13, 2020
- Breaking Contracts Over Coronavirus: Can You Argue ‘Act Of God’? General Counsel News, April 12, 2020
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 | | Robert Morris, M.D., Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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