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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
2,413,364 |
165,241 |
| US |
764,053 |
41,006 |
Antibody Epidemiology in LA LA Land A study has concluding that 4.1% of people in Los Angeles have antibodies to SARS-CoV-2 is noteworthy, but, among the epidemiological community, the response involves more consternation than fascination. The problem is that, despite the headlines, the authors have not published anything that could be called a study. They put out a press release with a result and no way to evaluate it..
Research News
Two studies demonstrate the importance of mild and asymptomatic disease, a German study introduces tools to study cellular immunity, a theory about TB vaccination is debunked, Israeli researchers propose using the virus to create herd immunity, and a review of internet websites demonstrates their lack or reliability early in the pandemic.
- A clinical study of 26 asymptomatic cases demonstrates that the CT changes in the lungs can be found even in asymptomatic patients and that viral carriage can last as long as 36 days.
- The potential for spread from asymptomatic and mildly symptomatic cases is demonstrated in a three family cluster, in which 8 of 15 members were infected, three had mild or no symptoms, but two of the three managed to transmit the disease to family members. Taken together, these two papers demonstrate the role of asymptomatic carriage in the spread of the disease and the challenge it poses for controlling the pandemic.
- German researchers offer a first detailed look at cellular immunity and provide tools for large scale testing, which will be essential in developing our understanding and assessment of immunity beyond simple antibody testing.
- A detailed look at the possibility that BCG vaccination (a vaccination for tuberculosis) might protect agains Covid-19 takes advantage of the fact that the year in which mandatory BCG vaccination was introduced in different countries creates a natural comparison group within each of those countries between age cohorts covered and not covered by requirements. The resulting analysis does not support the hypothesis, derived from more simplistic models, that it is protective against Covid-19.
- Israeli researchers consider the implications of a proposal that amounts, in essence, to using the active virus to vaccinate low risk populations and conclude that it would decrease overall mortality by 43% because it would help spare high risk populations.
- A review of websites providing information during the early stages of the epidemic found that, by one benchmark, 70% had a low score and none had a high score.
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*Preprint **Not peer reviewed.
- Covid19- Ahead of the Curve.
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Top News
- Epidemiological and clinical characteristics of 26 asymptomatic SARS-CoV-2 carriers Oxford Academic Journals: Coronavirus, April 22, 2020
- Transmission potential of asymptomatic and paucisymptomatic SARS-CoV-2 infections: a three-family cluster study in China Oxford Academic Journals: Coronavirus, April 22, 2020
- Presence of SARS-CoV-2 reactive T cells in COVID-19 patients and healthy donors MedRxiv Server for Health Sciences: Coronavirus, April 22, 2020
- Does TB Vaccination Reduce COVID-19 Infection?: No Evidence from a Regression Discontinuity Analysis MedRxiv Server for Health Sciences: Coronavirus, April 22, 2020
- Controlled Avalanche: A Regulated Voluntary Exposure Approach for Addressing Covid19 MedRxiv Server for Health Sciences: Coronavirus, April 22, 2020
- Misinformation of COVID-19 on the Internet: Infodemiology Study. NIH: National Library of Medicine: Coronavirus, April 22, 2020
Virology, Immunology, and Pathophysiology
- Response letter to Eosinophil count in severe coronavirus disease 2019 (COVID-19) Oxford Academic Journals: Coronavirus, April 21, 2020
- COVID-19 diagnosis and study of serum SARS-CoV-2 specific IgA, IgM and IgG by a quantitative and sensitive immunoassay MedRxiv Server for Health Sciences: Coronavirus, April 22, 2020
- Is Adipose Tissue a Reservoir for Viral Spread, Immune Activation and Cytokine Amplification in COVID‐19 Wiley: Coronavirus Research & News, April 21, 2020
Infection Control
- Responding to the COVID-19 outbreak in Singapore: Staff Protection and Staff Temperature and Sickness Surveillance Systems Infectious Diseases Society of America Journals: Coronavirus, April 21, 2020
- Interim evaluation of emergency declaration in Japan in the first week of the COVID-19 outbreak MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
- Reporting, Recording and Communication of COVID-19 Cases in Workplace: Data Protection as a Moving Target Oxford Academic Journals: Coronavirus, April 22, 2020
Clinical
- A case series of children with Coronavirus Disease 2019: what have we learned? Infectious Diseases Society of America Journals: Coronavirus, April 22, 2020
- Coronavirus (COVID-19) Outbreak: What the Department of Radiology Should Know. NIH: National Library of Medicine: Coronavirus, April 22, 2020
- Novel coronavirus COVID-19: an overview for emergency clinicians. NIH: National Library of Medicine: Coronavirus, April 22, 2020
Epidemiology
- Epidemiological trends of COVID‐19 epidemic in Italy during March 2020. From 1,000 to 100,000 cases Wiley: Coronavirus Research & News, April 21, 2020
- Self-reported COVID-19 symptoms on Twitter: An analysis and a research resource MedRxiv Server for Health Sciences: Coronavirus, April 22, 2020
- How many are at increased risk of severe COVID-19 disease? Rapid global, regional and national estimates for 2020 MedRxiv Server for Health Sciences: Coronavirus, April 22, 2020
- COVID-19: An Update on the Epidemiological, Genomic Origin, Phylogenetic study, India centric to Worldwide current status MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
Modeling and Prediction
- Tracing DAY-ZERO and Forecasting the Fade out of the COVID-19 Outbreak in Lombardy, Italy: A Compartmental Modelling and Numerical Optimization Approach. MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
- Chinese and Italian COVID-19 outbreaks can be correctly described by a modified SIRD model MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
- Applying the unified models of ecology to forecast epidemics, with application to Covid-19 MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
Review and Commentary
- COVID-19: The outbreak caused by a new coronavirus. NIH: National Library of Medicine: Coronavirus, April 22, 2020
- Coronavirus Diseases (COVID-19) Current Status and Future Perspectives: A Narrative Review. NIH: National Library of Medicine: Coronavirus, April 22, 2020
- COVID-19 (Novel Coronavirus 2019) - recent trends. NIH: National Library of Medicine: Coronavirus, April 22, 2020
Mental Health
- Psychological stress of medical staffs during outbreak of COVID‐19 and adjustment strategy Wiley: Coronavirus Research & News, April 21, 2020
Basic Science
- A Droplet Microfluidic Platform for High-Throughput Photochemical Reactions ChemRxiv, April 22, 2020
- Compound Collections at KU 1947-2017: Cheminformatic Analysis and Computational Protein Target Prediction ChemRxiv, April 22, 2020
- Determining the Geographical Origin of Crude Palm Oil with the Combined Use of GC-IMS Fingerprinting and Chemometrics ChemRxiv, April 22, 2020
Other
- COVID-19, City Lockdowns, and Air Pollution: Evidence from China MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
New Clinical Trials
- AiM COVID for Covid 19 Tracking and Prediction April 21, 2020
- Opportunistic Screening for Asymptomatic Left Ventricular Dysfunction in Coronavirus Disease 2019 (COVID19) Survivors April 21, 2020
- CoVID-19 Plasma in Treatment of COVID-19 Patients April 21, 2020
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Coronavirus Research Resources
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China
- Transmission potential of asymptomatic and paucisymptomatic SARS-CoV-2 infections: a three-family cluster study in China Oxford Academic Journals: Coronavirus, April 22, 2020
- Did Trump ship 17 tons of ‘American’ masks and medical supplies to China? Washington Post: Coronavirus, April 22, 2020
- Chinese and Italian COVID-19 outbreaks can be correctly described by a modified SIRD model MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
South Korea
- Live updates: Virus death toll tops 1,000 in region; Hogan responds to Trump criticism over South Korean kits; spelling bee canceled Washington Post: Coronavirus, April 21, 2020
- Maryland Buys 500,000 Test Kits From South Korea, Drawing Criticism From Trump NPR: Health, April 21, 2020
- SEOUL, South Korea (AP) — South Korean officials reported no unusual activity in North Korea on Tuesday following unconfirmed media reports that leader Kim Jong Un was in fragile health after... AP Health News: Coronavirus, April 21, 2020
Italy
- Tracing DAY-ZERO and Forecasting the Fade out of the COVID-19 Outbreak in Lombardy, Italy: A Compartmental Modelling and Numerical Optimization Approach. MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
- Chinese and Italian COVID-19 outbreaks can be correctly described by a modified SIRD model MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
- Challenges in the Care of IBD Patients During the CoViD-19 Pandemic: Report From a “Red Zone” Area in Northern Italy Oxford Academic Journals: Coronavirus, April 21, 2020
- A Frail Health Care System for an Old Population: Lesson form the COVID-19 Outbreak in Italy Oxford Academic Journals: Coronavirus, April 21, 2020
- Italy Finally Sees Its 1st Drop In Active Coronavirus Cases NPR: Health, April 21, 2020
- Ravaged by the coronavirus, Italy tiptoes shakily toward reopening economy NBC News: Coronavirus Latest News, April 21, 2020
Spain
- COPENHAGEN (AP) — Spain canceled the Running of the Bulls in July, the U.S. scrapped the national spelling bee in June and Germany even called off Oktoberfest, making it clear Tuesday that the... AP Health News: Coronavirus, April 21, 2020
Germany
- Germany Is Conducting Nationwide COVID-19 Antibody Testing NPR: Health, April 21, 2020
- COPENHAGEN (AP) — Spain canceled the Running of the Bulls in July, the U.S. scrapped the national spelling bee in June and Germany even called off Oktoberfest, making it clear Tuesday that the... AP Health News: Coronavirus, April 21, 2020
France
- AP PHOTOS: On French quarantine isles, virus echoes the past By DANIEL COLEApril 22, 2020 GMT AP Health News: Coronavirus, April 22, 2020
- France Looking Into Setting Up Insurance Cover for Pandemics New York Times: Coronavirus, April 22, 2020
- PARIS (AP) — Confusion reigns in French soccer as to whether the league should resume amid the coronavirus pandemic. The co-president of the French professional soccer players' union called... AP Health News: Coronavirus, April 21, 2020
- Lives Lost: Boss, bottle washer and heartbeat of French bar AP Health News: Coronavirus, April 21, 2020
- PARIS (AP) — Paris police are facing a modest uptick of unrest in the oft-troubled suburbs of the locked-down French capital, making a small number of arrests after fires were set and fireworks... AP Health News: Coronavirus, April 21, 2020
- After Lockdown, French Kids Back to School in Smaller Classes New York Times: Coronavirus, April 21, 2020
United Kingdom
- Police in English Town Warn Public About Man With Weapon: BBC New York Times: Coronavirus, April 22, 2020
- Estimates of regional infectivity of COVID-19 in the United Kingdom following imposition of social distancing measures MedRxiv Server for Health Sciences: Coronavirus, April 21, 2020
- Ronan O'Rahilly: pirate radio's godfather made a sea change in British pop | Alexis Petridis The Guardian (U.K.) - Opinions: Coronavirus, April 21, 2020
Other International News
- Lockdown reveals fresh air, cleaner rivers in India AP Health News: Coronavirus, April 22, 2020
- THE HAGUE, Netherlands (AP) — A village of 4,000 people in the southern Netherlands was evacuated early Wednesday as smoke from a wildfire in a nearby national park drifted over homes, authorities... AP Health News: Coronavirus, April 22, 2020
- TEL AVIV, Israel (AP) — The normally bustling city of Tel Aviv, famed for its nightlife and rowdy beachfront, has fallen eerily quiet due to Israel's tight restrictions on movement that are meant... AP Health News: Coronavirus, April 22, 2020
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Business and Economic News
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Business News
- Some US governors move to reopen their states, though some local leaders are pushing back CNN.com - Health, April 22, 2020
- Doctors try to untangle why they're seeing 'unprecedented' blood clotting among Covid-19 patients CNN.com - Health, April 22, 2020
- NIH Covid-19 treatment guidelines warn against drug combo pushed by Trump CNN.com - Health, April 22, 2020
Economics Blogs
- COVID-19 in Italy: An analysis of death registry data VoxEU.org, April 22, 2020
- Covid-19: Employment in middle-income economies VoxEU.org, April 22, 2020
- COVID-19, employment and women in OECD countries VoxEU.org, April 22, 2020
Top Economics News
- Doctors: Execution drugs could help COVID-19 patients - KPIC News (Brazilian Economy), April 22, 2020
- Coronavirus: Oil plunges for a second day on gloomy outlook BBC: Economy, April 22, 2020
- President Trump at odds with Gov. Hogan over COVID tests - Fox Baltimore (Trump Economy), April 22, 2020
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Law Technology
- Press Release Neudesic Streamlines CDC Reporting Requirements with Free COVID-19 Case Management Tracker Category: Application Development IRVINE, CA – April 15, 2020 — Neudesic, LLC, a nationally recognized business and technology consulting firm, … Read more Neudesic, April 22, 2020
- COVID-19 and climate change IT Governance Blog, April 22, 2020
- US Judge Won't Force Open Coronavirus Relief to Lobbyists, Political Consultants Blog of Legal Times, April 22, 2020
Legal Administrator
- COVID-19 Disrupts the Hiring Landscape EntertainHR, April 22, 2020
- US Judge Won't Force Open Coronavirus Relief to Lobbyists, Political Consultants Blog of Legal Times, April 22, 2020
- State of Legal Sector in Coronavirus Times - Tech, Instead of Layoffs, Pay Cycle Law and More, April 21, 2020
Librarian News
- UK: Covid-19 testing extended to frontline court staff and judges House of Butter, April 22, 2020
- Mondaq’s Latest (Wait For It) 94 Law Firm COVID-19 Articles From Around The World House of Butter, April 22, 2020
- 10-minute guide to Singapore’s COVID-19 (Temporary Measures) Act House of Butter, April 22, 2020
Leading Law Departments
- Starting Remotely During COVID-19 Joe Borstein - Pangea3 - Blog, April 22, 2020
- Law Firm Responses to the COVID-19 Crisis: Current Actions & Future Challenges Legal Executive Institute: Blog, April 21, 2020
- Covid-19 Crisis: What About ICFR? CorporateCounsel.net Blog, April 21, 2020
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 | | Robert Morris, M.D., Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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