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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
2,413,364 |
165,241 |
| US |
764,053 |
40,707 |
Research News
Poor preparation forced the use of costly intervention strategies, people with symptoms are not staying home, studies of droplets do not support the 6 foot social distance, travel restrictions can limit spread, antibodies take 20 days to fully develop, telemedicine use has more than doubled, and South Korea's contact tracing tool required massive integration of data systems.
- A review of the available literature** on the cost and effectiveness of infection control strategies concludes that the classic model of contact tracing and case isolation, together with hand hygiene, face masks, and PPE for health care workers are the most cost effective strategies. In this case, the high cost strategies of social distancing and school closures were made necessary by lack of preparedness.
- A questionnaire based study** finds that the presence of COVID-19 symptoms is not reducing the probability that respondents will leave their home, pointing to a dire need for public health education.
- A review of the available evidence on airborne* droplets and aerosols points out the flaws in the simplistic social distancing guidelines and demonstrates the need to investigate this issue more carefully. Eight of ten studies showed droplets traveling more than six feet. The studies do not address the question of the infectivity of these droplets.
- A Chinese study** demonstrates the impact of travel restrictions, particularly from Wuhan, on the incidence of disease in other Chinese cities.
- A study of antibodies to SARS-CoV-2** in 221 patients showed a peak in IgG at 19-21 days after initial symptoms with a subsequent decline that calls for further investigation.
- An analysis of telemedicine usage* at NYU hospitals found a 135% increase in usage for urgent care since the pandemic began. It seems likely that this will greatly expand its use even after the disease has declined.
- An overview of South Korea's IT based contact tracing system shows both the extent of systems that were employed and the challenges addressed in creating the system.
* * * * *
*Accepted, pre-publication **Not peer reviewed.
- Covid19- Ahead of the Curve.
* * * * *
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Top News
- Evidence-based, cost-effective interventions to suppress the COVID-19 pandemic: a rapid systematic review MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
- The association between age, COVID-19 symptoms, and social distancing behavior in the United States MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Airborne or droplet precautions for health workers treating COVID-19? Infectious Diseases Society of America Journals: Coronavirus, April 24, 2020
Virology, Immunology, and Pathophysiology
- Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Neutralizing Antibodies Responses to SARS-CoV-2 in COVID-19 Inpatients and Convalescent Patients MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Profile of RT-PCR for SARS-CoV-2: a preliminary study from 56 COVID-19 patients Infectious Diseases Society of America Journals: Coronavirus, April 23, 2020
Infection Control
- Social interventions can lower COVID-19 deaths in middle-income countries MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Modest effects of contact reduction measures on the reproduction number of SARS-CoV-2 in the most affected European countries and the US MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
- Effect of emergency declaration for the COVID −19 outbreak in Tokyo, Japan in the first two weeks MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
Clinical
- Clinical characteristics of imported and second-generation COVID-19 cases outside Wuhan, China: A multicenter retrospective study MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Influence of blood pressure on pneumonia risk: Epidemiological association and Mendelian randomisation in the UK Biobank MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Clinical and Imaging Findings in COVID-19 Patients Complicated by Pulmonary Embolism MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
Epidemiology
- The changing patter of COVID-19 in China: A tempo-geographic analysis of the SARS-CoV-2 epidemic Infectious Diseases Society of America Journals: Coronavirus, April 23, 2020
- Epidemiology of COVID-19. NIH: National Library of Medicine: Coronavirus, April 23, 2020
- Epidemiological characteristics of COVID-19 in medical staff members of neurosurgery departments in Hubei province: A multicentre descriptive study MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
Modeling and Prediction
- In-host Modelling of COVID-19 Kinetics in Humans Outbreak Science, April 23, 2020
- Estimating the reproduction number of COVID-19 in Iran using epidemic modeling MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Modeling quarantine during epidemics and mass-testing using drones MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Estimation of Tunisia COVID-19 infected cases based on mortality rate MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Impact of control strategies on COVID-19 pandemic and the SIR model based forecasting in Bangladesh. MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- ARIMA modelling of predicting COVID-19 infections MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
Review and Commentary
- Lessons learned from HIV can inform our approach to COVID‐19 stigma Wiley: Coronavirus Research & News, April 24, 2020
- Weight Stigma and the “Quarantine‐15” Wiley: Coronavirus Research & News, April 24, 2020
- Lifestyle behaviours during the COVID‐19 – time to connect Wiley: Coronavirus Research & News, April 24, 2020
Mental Health
- Covid‐19: Supporting nurses’ psychological and mental health Wiley: Coronavirus Research & News, April 24, 2020
Basic Science
- Identification of Potent Inhibitors of COVID-19 Main Protease Enzyme by Molecular Docking Study ChemRxiv, April 24, 2020
- Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs ChemRxiv, April 24, 2020
- Multi-Targeting of Functional Cysteines in Multiple Conserved SARS-CoV-2 Domains by Clinically Safe Zn-ejectors ChemRxiv, April 24, 2020
Other
- Medical genetics education in the midst of the COVID‐19 pandemic: Shared resources Wiley: Coronavirus Research & News, April 24, 2020
- Misinformation of COVID-19 on the Internet: Infodemiology Study. NIH: National Library of Medicine: Coronavirus, April 23, 2020
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Coronavirus Research Resources
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China
- Understanding the Collective Responses of Populations to the COVID-19 Pandemic in Mainland China MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
- A Tool to Early Predict Severe Corona Virus Disease 2019 (COVID-19) : A Multicenter Study using the Risk Nomogram in Wuhan and Guangdong, China Infectious Diseases Society of America Journals: Coronavirus, April 23, 2020
- The changing patter of COVID-19 in China: A tempo-geographic analysis of the SARS-CoV-2 epidemic Infectious Diseases Society of America Journals: Coronavirus, April 23, 2020
Iran
- Estimating the reproduction number of COVID-19 in Iran using epidemic modeling MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- Iran Hopes Slowing Rise Of COVID-19 Cases Means The Worst Is Over NPR: Health, April 23, 2020
Italy
- Gastrointestinal symptoms as Covid-19 onset in hospitalized Italian patients MedRxiv Server for Health Sciences: Coronavirus, April 23, 2020
- The Latest: Hard-hit region in Italy shows virus growth AP Health News: Coronavirus, April 23, 2020
- Italy Eyes Budget Gap Around 10% of GDP in 2020, Above 3% in 2021: Source New York Times: Coronavirus, April 23, 2020
Spain
- MADRID (AP) — The Spanish league wants all players and coaches tested daily for the coronavirus when trainings resume. The information is on a league protocol to which The Associated Press... AP Health News: Coronavirus, April 23, 2020
Germany
- BERLIN (AP) — German Chancellor Angela Merkel called Thursday for international cooperation on the development of a vaccination for the new coronavirus, saying that the pandemic transcends borders... AP Health News: Coronavirus, April 23, 2020
United Kingdom
- SELSTON, England (AP) — Lucy Dawson is haunted by a sense of powerlessness. The nurse has equipment to treat the residents of the nursing home where she works when they become sick with the... AP Health News: Coronavirus, April 24, 2020
- Testing of an experimental COVID-19 vaccine began in healthy volunteers in Britain Thursday, the latest in a cluster of early-stage studies in search of protection against the coronavirus.... AP Health News: Coronavirus, April 23, 2020
Other International News
- The Latest: Sweden warns businesses not social distancing AP Health News: Coronavirus, April 24, 2020
- Malaysia Reports 88 New Coronavirus Cases and One New Death New York Times: Coronavirus, April 24, 2020
- Responding to the COVID-19 outbreak in Singapore: Staff Protection and Staff Temperature and Sickness Surveillance Systems Infectious Diseases Society of America Journals: Coronavirus, April 23, 2020
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Business and Economic News
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Business News
- Preliminary antibody testing in New York suggests much wider spread of coronavirus CNN.com - Health, April 24, 2020
- Remdesivir trial posted online prematurely was 'inconclusive,' Gilead says CNN.com - Health, April 24, 2020
- No need to wipe down groceries or takeout, experts say, but do wash your hands CNN.com - Health, April 24, 2020
Economics Blogs
- Abbreviated Coronavirus dashboard for April 23: New York accounts for ALL of the US’s progress Angry Bear, April 24, 2020
- Keeping firms afloat during the COVID-19 crisis VoxEU.org, April 24, 2020
- Short-term forecasting of the coronavirus pandemic VoxEU.org, April 24, 2020
Top Economics News
- Coronavirus pandemic reverses Brazil's economic course - Buenos Aires Times (Brazilian Economy), April 24, 2020
- Could the Covid crisis be an economic opportunity for Brexit Britain? - Spectator.co.uk (Brexit Economy News), April 24, 2020
- Can Europe be brought closer by its coronavirus response? | Latest Brexit news and top stories - The New European (Brexit Economy News), April 24, 2020
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Law Technology
- Amid COVID-19 Shutdowns, Pork Giant Smithfield Foods Sued by Worker Group Blog of Legal Times, April 24, 2020
- COVID-19: What are people buying during this pandemic? Vable Blog, April 24, 2020
- COVID-19: 8 ways to keep communication channels open Vable Blog, April 24, 2020
Legal Administrator
- Amid COVID-19 Shutdowns, Pork Giant Smithfield Foods Sued by Worker Group Blog of Legal Times, April 24, 2020
- WilmerHale's Matthew Martens on Religious Liberty, More Hours and 'Drowning in Email' During COVID-19 Blog of Legal Times, April 23, 2020
- How Hogan Lovells Has Lobbied for Saudi Arabia During Coronavirus Crisis Blog of Legal Times, April 23, 2020
Librarian News
- More Food & COVID Law, This Time France: France allows changes to raw milk regulations because of coronavirus House of Butter, April 24, 2020
- Amid COVID-19 Shutdowns, Pork Giant Smithfield Foods Sued by Worker Group law.com: Newswire, April 24, 2020
- WilmerHale's Matthew Martens on Religious Liberty, More Hours and 'Drowning in Email' During COVID-19 law.com: Newswire, April 24, 2020
Leading Law Departments
- Giving Tuesday’s Emergency Response to the COVID-19 Crisis BoardEffect Blog, April 23, 2020
- Out of Sight, Not Out of Mind: Prosecutors Won’t Overlook Remote Wrongdoing in COVID-19 Times Inside Counsel, April 23, 2020
- Neb. Senator’s COVID-19 Bill Would Give Pharmaceuticals 10 Additional Years of Patent Protection Today's General Counsel: Career, April 23, 2020
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 | | Robert Morris, M.D., Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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