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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
2,413,364 |
165,241 |
| US |
764,053 |
40,707 |
The US Had the Least Effective Response to the Pandemic of Any Country in the World That scathing indictment is buried in the back of a preprint of an article by Mexican researchers focused on the role of temperature in limiting the spread of disease, which barely mentions the bombshell in Figure 5. Let's unpack it.
Research News
SUMMARY
- The rate of undiagnosed SARS-CoV-2 infections is 18 times higher among health care workers as compared to non-health care workers in a University setting.
- A cohort of 33 COVID-19 pneumonia patients continued to shed virus for as long as seven weeks in stool in sputum and stool samples, long after throat swabs were negative.
- A study of residents of the Seattle nursing home that experienced the first major outbreak in the US demonstrates that infection-control strategies focused solely on symptomatic residents were not sufficient to prevent transmission of SARS-CoV-2 within the facility.
- A metabolomic and lipidomic study of COVID-19 patients suggests there may be previously unrecognized associations with lipid metabolism and hepatic function in this disease.
- Elevated troponin levels on admission are strongly associated with mortality in COVID-19 patients. Troponin is a marker of cardiac injury.
- Social distancing estimates derived from cell phone data may substantially improve modeling predictions from the widely used IHME models.
- All five household contacts of a health care worker in Wuhan with COVID-19 developed asymptomatic disease, consistent with a growing body of evidence that a high percentage of infections are asymptomatic.
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*Preprint **Not peer reviewed.
- Covid19- Ahead of the Curve.
* * * * *
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Diagnosis
- Using ILI surveillance to estimate state-specific case detection rates and forecast SARS-CoV-2 spread in the United States MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Analytical sensitivity and efficiency comparisons of SARS-COV-2 qRT-PCR primer-probe sets MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Research on CNN-based Models Optimized by Genetic Algorithm and Application in the Diagnosis of Pneumonia and COVID-19 MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
Emergency Care and Triage
- COVID‐19 and emergency surgery Wiley: Coronavirus Research & News, April 27, 2020
Infection Control
- Autopsy in suspected COVID-19 cases. NIH: National Library of Medicine: Coronavirus, April 25, 2020
- Assessment of N95 respirator decontamination and re-use for SARS-CoV-2 MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
- Asymptomatic SARS‐CoV‐2 infected case with viral detection positive in stool but negative in nasopharyngeal samples lasts for 42 days Wiley: Coronavirus Research & News, April 27, 2020
- Asymptomatic COVID‐19 infection in late pregnancy indicated no vertical transmission Wiley: Coronavirus Research & News, April 27, 2020
- First reported nosocomial outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a pediatric dialysis unit Infectious Diseases Society of America Journals: Coronavirus, April 27, 2020
Medical Therapy
- The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID-19 MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. NIH: National Library of Medicine: Coronavirus, April 25, 2020
- Risk of drug-induced Long QT Syndrome associated with the use of repurposed COVID-19 drugs: a systematic review MedRxiv Server for Health Sciences: Coronavirus, April 25, 2020
ICU Care
- High prevalence of putative invasive pulmonary aspergillosis in critically ill COVID-19 patients MedRxiv Server for Health Sciences: Coronavirus, April 25, 2020
- Management of COVID-19 Respiratory Distress JAMA Network: Coronavirus, April 24, 2020
- Transforming ORs into ICUs New England Journal of Medicine: Coronavirus, April 24, 2020
- ICU and ventilator mortality among critically ill adults with COVID-19 MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
Clinical Course and Outcomes
- Clinical Characteristics of Hospitalized Covid-19 Patients in New York City MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Inequality in acute respiratory infection outcomes in the United States: A review of the literature and its implications for public health policy and practice. MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- COVID-19 with spontaneous pneumothorax,pneumomediastinum and subcutaneous emphysema Oxford Academic Journals: Coronavirus, April 24, 2020
Impact on Other Specialties
- Letter: The Risk of COVID-19 Infection During Neurosurgical Procedures: A Review of Severe Acute Respiratory Distress Syndrome Coronavirus 2 (SARS-CoV-2) Modes of Transmission and Proposed Neurosurgery-Specific Measures for Mitigation Oxford Academic Journals: Coronavirus, April 26, 2020
- Letter: COVID-19 Pandemic: Safety Precautions for Stereotactic Radiosurgery Oxford Academic Journals: Coronavirus, April 26, 2020
- Letter: Maintaining Neurosurgical Resident Education and Safety During the COVID-19 Pandemic Oxford Academic Journals: Coronavirus, April 26, 2020
Reviews, Commentary, and Miscellaneous
- A Review of Coronavirus Disease-2019 (COVID-19). NIH: National Library of Medicine: Coronavirus, April 25, 2020
- COVID-19: The outbreak caused by a new coronavirus. NIH: National Library of Medicine: Coronavirus, April 24, 2020
- Access by English and Non-English Speakers Is Needed to COVID-19Â Clinical Trials Infectious Diseases Society of America Journals: Coronavirus, April 27, 2020
Newly Registered Clinical Trials
- Indirect Endovenous Systemic Ozone for New Coronavirus Disease (COVID19) in Non-intubated Patients April 24, 2020
- Efficacy of Various Doses of Hydroxychloroquine in Pre-Exposure Prophylaxis for COVID 19 April 24, 2020
- Estrogen Patch for COVID-19 Symptoms April 24, 2020
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BASIC SCIENCE AND EPIDEMIOLOGY
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Virology, Immunology, and Pathophysiology
- Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD Oxford Academic Journals: Coronavirus, April 25, 2020
- Whole Genome Sequence Analysis and Homology Modelling of a 3C Like Peptidase and a Non-Structural Protein 3 of the SARS-CoV-2 Shows Protein Ligand Interaction with an Aza-Peptide and a Noncovalent Lead Inhibitor with Possible Antiviral Properties ChemRxiv, April 24, 2020
- Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses Outbreak Science, April 27, 2020
Vaccine Development
- Is there evidence that BCG vaccination has non-specific protective effects for COVID 19 infections or is it an illusion created by lack of testing? MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
Epidemiology
- Decline in global COVID-19 transmission MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Measure what matters: counts of hospitalized patients are a better metric for health system capacity planning for a reopening MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Links between air pollution and COVID-19 in England Outbreak Science, April 26, 2020
Modeling and Prediction
- Surge capacities and predicted demands of Brazil's health system associated with severe COVID-19 cases MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- A statistical forecast of LOW mortality and morbidity due to COVID-19, in ARGENTINA and other Southern Hemisphere countries. MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Forecasting the impact of the first wave of the COVID-19 pandemic on hospital demand and deaths for the USA and European Economic Area countries MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
Public Health Intervention
- Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19: a modelling study MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Adaptive cyclic exit strategies from lockdown to suppress COVID-19 and allow economic activity MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- COVID-19 Epidemic in Algeria: Assessment of the implemented preventive strategy MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
Mental Health
- Child Abuse Awareness Month During the Coronavirus Disease 2019 Pandemic JAMA Network: Coronavirus, April 24, 2020
- Mental Health Status Among Children in Home Confinement During the Coronavirus Disease 2019 Outbreak in Hubei Province, China JAMA Network: Coronavirus, April 24, 2020
- Survey: BH organizations closing programs, reducing staff amid pandemic Wiley: Coronavirus Research & News, April 27, 2020
- Psychological distress found among exposed health care workers Wiley: Coronavirus Research & News, April 27, 2020
Other
- Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19). NIH: National Library of Medicine: Coronavirus, April 25, 2020
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. NIH: National Library of Medicine: Coronavirus, April 25, 2020
- The outbreak of COVID-19: An overview. NIH: National Library of Medicine: Coronavirus, April 25, 2020
- COVID-19 in Iran, a comprehensive investigation from exposure to treatment outcomes MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
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Coronavirus Research Resources
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China
- China Reports 11 New Coronavirus Cases, No Deaths on Saturday New York Times: Coronavirus, April 25, 2020
- Meteorological factors correlate with transmission of 2019-nCoV: Proof of incidence of novel coronavirus pneumonia in Hubei Province, China MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
- Reporting the life tracks of confirmed cases can effective prevent and control the COVID-19 outbreak in China MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
Iran
- One thing the virus hasn’t changed: Iran and the U.S. still hate each other Washington Post: Coronavirus, April 25, 2020
- COVID-19 in Iran, a comprehensive investigation from exposure to treatment outcomes MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
Italy
- BARCELONA, Spain (AP) — Shrieks of joy rang out in the streets of Spain as children were allowed to go outside and play Sunday for first time in six weeks, while people in Italy and France were... AP Health News: Coronavirus, April 26, 2020
- Italy's Daily Coronavirus Death Toll Lowest Since March 14, New Cases Fall New York Times: Coronavirus, April 26, 2020
- ROME (AP) — As Italy prepares to emerge from the West’s first and most extensive coronavirus lockdown, it is increasingly clear that something went terribly wrong in Lombardy, the hardest-hit... AP Health News: Coronavirus, April 26, 2020
- In Italy, 'Suspended Shopping' Helps Those Facing Economic Hardship During Pandemic NPR: Health, April 24, 2020
- Italy's Prime Minister Announces Gradual Easing Of COVID-19 Lockdown NPR: Health, April 27, 2020
Spain
- BARCELONA, Spain (AP) — Shrieks of joy rang out in the streets of Spain as children were allowed to go outside and play Sunday for first time in six weeks, while people in Italy and France were... AP Health News: Coronavirus, April 26, 2020
- MADRID (AP) — Spain’s health minister said Sunday that Spaniards should not expect to see professional soccer restart before the summer. Spain has been without soccer since March 12, two... AP Health News: Coronavirus, April 26, 2020
- Spanish flu-era diaries give Ohio family hope NBC News: Coronavirus Latest News, April 26, 2020
Germany
- German Government Divided Over Form of Lufthansa Rescue Deal New York Times: Coronavirus, April 26, 2020
- German Labour Minister Wants to Put Right to Home Working in Law New York Times: Coronavirus, April 26, 2020
France
- BARCELONA, Spain (AP) — Shrieks of joy rang out in the streets of Spain as children were allowed to go outside and play Sunday for first time in six weeks, while people in Italy and France were... AP Health News: Coronavirus, April 26, 2020
- LE PECQ, France (AP) — The itch to dance, to break out of coronavirus lockdown and bust a few moves in the fresh air, out on the street, has proved too strong for some to resist in Paris after... AP Health News: Coronavirus, April 26, 2020
- CLICHY-SOUS-BOIS, France (AP) — Joining more than 1,000 others, Djemba Diatite stood for hours in line to feed her growing family, grateful for handouts of fruits, vegetables and soap. It was her... AP Health News: Coronavirus, April 26, 2020
- Analysis of the COVID-19 epidemic in french overseas department Mayotte based on a modified deterministic and stochastic SEIR model MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
- Estimating the burden of SARS-CoV-2 in France MedRxiv Server for Health Sciences: Coronavirus, April 24, 2020
- 2nd French Court Orders Amazon to Better Protect Workers New York Times: Coronavirus, April 24, 2020
United Kingdom
- LONDON (AP) — British Prime Minister Boris Johnson is returning to work after recovering from a coronavirus infection that put him in intensive care, with his government facing growing criticism... AP Health News: Coronavirus, April 26, 2020
- The Latest on the effects of the coronavirus outbreak on sports around the world: ___ Premier League club Everton says it is “appalled” striker Moise Kean flouted the British... AP Health News: Coronavirus, April 26, 2020
- British pubs are closed, but Brits won’t give up their pub quizzes Washington Post: Coronavirus, April 26, 2020
Other International News
- Surge capacities and predicted demands of Brazil's health system associated with severe COVID-19 cases MedRxiv Server for Health Sciences: Coronavirus, April 26, 2020
- Touch a shadow, "You're it!": New routines as Denmark returns to school NBC News: Coronavirus Latest News, April 26, 2020
- HARLINGEN, Netherlands (AP) — Greeted by relieved parents, pet dogs, flares and a cloud of orange smoke, a group of 25 Dutch high school students with very little sailing experience ended a... AP Health News: Coronavirus, April 26, 2020
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Business and Economic News
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Business News
- One Man's Radical Plan to Solve Wealth Inequality Wired.com, April 26, 2020
- The Shared Visual Language of the 1918 and 2020 Pandemics Wired.com, April 26, 2020
- 16 Best Couch Co-Op Games (2020): PS4, Xbox One, PC, Switch Wired.com, April 26, 2020
Economics Blogs
- COVID-Economics Links (April 26) Antonio Fatas and Ilian Mihov on the Global Economy, April 26, 2020
- Covid-induced innovation in the business world Marginal Revolution, April 26, 2020
- The State of Money Supply Growth Since the Start of COVID-19 Panic Economic Policy Journal, April 26, 2020
Top Economics News
- SUNDAY CONVERSATION: Judge Lina Hidalgo discusses COVID-19 response, growing up in Katy - Chron (Colombian Economy), April 26, 2020
- Coronavirus lockdown: Where’s the wobble room? Gulf News: Business Economy, April 26, 2020
- COVID-19 jobless rates will be comparable to Great Depression: Trump economic adviser - ABC News (Trump Economy), April 26, 2020
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Law Technology
- A practical way for CIOs to manage IT costs through the COVID-19 crisis McKinsey Insights & Publications, April 26, 2020
- Our offices will never be the same after COVID-19. Here’s what they could look like Stephen's Lighthouse, April 26, 2020
- A global view of how consumer behavior is changing amid COVID-19 McKinsey Insights & Publications, April 25, 2020
Legal Administrator
- COVID-19: Death, Truth, Faith, And Love TaxProf Blog, April 26, 2020
- Law Firms - Experts Opine on What It Will Take to Get Through 2020 Crisis (but how much do we trust expert opinion in COVID-19?) Law and More, April 25, 2020
- Chase Bank, Ruth's Chris Sued Over COVID-19 Relief Loans Blog of Legal Times, April 24, 2020
Librarian News
- What You Should Know About Online Tools During the COVID-19 Crisis beSpacific, April 26, 2020
- New Title: (USA) Employer’s Guide to COVID-19 and Emerging Workplace Issues House of Butter, April 26, 2020
- Stanford Law School Launches COVID-19 Discussions Series House of Butter, April 26, 2020
Leading Law Departments
- CCPA Concerns in the Rush for COVID-19 Tracking Exterro Blog, April 24, 2020
- Big Banks Accused of Favoring More Lucrative Small Business Loans in Coronavirus Program General Counsel News, April 24, 2020
- EEOC Technical Guidance on COVID-19 Blog: Workplace Prof Blog, April 24, 2020
- Improving Your Job Prospects Post-Coronavirus Inhouse Blog, April 27, 2020
- The Lives of Lawyers: Rethinking What Is “Essential” for Lawyers in the Age of Coronavirus Zero: News and Insights, April 27, 2020
- The Impact of COVID-19 on Financial Contracts General Counsel News, April 26, 2020
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 | | Robert Morris, M.D., Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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