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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
3,798,021 |
262,969 |
| US |
1,252,110 |
73,769 |
Data from worldmeters.info
Research News
A risk assessment likely to get substantial attention** compares the risk of death from COVID-19 to the risk from dying in a traffic fatality. Although this sort of risk comparison is important and valuable as we make difficult decisions about ending strict social distancing, the study has two major limitations: 1) it considers death as the only negative consequence of the disease without considering the potential severe and prolonged nature of the disease and its sequelae among survivors, 2)it focuses exclusively on those under age 65, when they are the group least likely to die from the disease, a strange choice given the ease with which they could have included analyses for other age groups. The authors argue appropriately for increased protection for older people, but part of the reason for reducing infection in younger age groups is specifically to protect more vulnerable groups.
A compilation of 50 studies on COVID-19 in pregnancy** found an 8% infection rate among infants of infected mothers and a 25% rate of preterm birth, suggesting pregnant women should exercise extreme caution, particularly in the third trimester of pregnancy.
A new approach to viral detection** based on droplet digital PCR (ddPCR) appears to be far more sensitive than RT-PCR and suggests that the virus is present longer than previously believed, a finding with important implications for quarantine protocols.
A simulation model compares** the relative effectiveness of a 1-layer (primary contacts only) and 2-layer (primary contacts and their primary contacts) quarantine and concludes that rapid detection (within one week) of cases might allow 1-layer quarantine, but slower detection will require 2-layer quarantine to prevent rapid growth of the outbreak.
A report from Bergamo Italy chronicles the toll of the outbreak on health care providers including the deaths of 19 physicians and suggests that an urgent, region-wide lockdown would have been necessary early in the epidemic to prevent the devastation that the city endured.
An analysis of air pollution and COVID-19** in the Netherlands finds a strong association between fine airborne particles and both disease incidence and related hospital admissions. The authors suggest that air pollution levels should be considered in mitigation strategies for the disease.
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*Preprint **Not peer reviewed.
Covid19- Ahead of the Curve.
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Top News
- Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Pregnancy outcomes, Newborn complications and Maternal-Fetal Transmission of SARS-CoV-2 in women with COVID-19: A systematic review of 441 cases MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- ddPCR: a more sensitive and accurate tool for SARS-CoV-2 detection in low viral load specimens MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Prevent the resurgence of infectious disease with asymptomatic carriers MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Adaptations and Lessons in the Province of Bergamo New England Journal of Medicine: Coronavirus, May 5, 2020
- Incidence of COVID-19 and Connections with Air Pollution Exposure: Evidence from the Netherlands Outbreak Science, May 5, 2020
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Clinical Laboratory and Diagnostics
- Rapid development of COVID-19 rapid diagnostics for low resource settings: accelerating delivery through transparency, responsiveness, and open collaboration MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
Infection Control
- Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- SARS-CoV-2 human disinfection chambers: a critical analysis Oxford Academic Journals: Coronavirus, May 6, 2020
Clinical Case Management
- Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19) JAMA Network: Coronavirus, May 5, 2020
- Understanding Observational Treatment Comparisons in the Setting of Coronavirus Disease 2019 (COVID-19) JAMA Network: Coronavirus, May 5, 2020
- Use of telemedicine to provide clinical pharmacy services during the SARS-CoV-2 pandemic Oxford Academic Journals: Coronavirus, May 5, 2020
- Prolonged aPTT in Patients with Covid-19 New England Journal of Medicine: Coronavirus, May 5, 2020
Impact on Other Specialties
- Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas Oxford Academic Journals: Coronavirus, May 5, 2020
- Letter: News From the COVID-19 Front Lines: How Neurosurgeons Are Contributing Oxford Academic Journals: Coronavirus, May 6, 2020
- Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine. NIH: National Library of Medicine: Coronavirus, May 6, 2020
- Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. NIH: National Library of Medicine: Coronavirus, May 6, 2020
- COVID-19 Pandemic and Beyond: Considerations and Costs of Telehealth Exercise Programs for Older Adults With Functional Impairments Living at Home—Lessons Learned from a Pilot Case Study Oxford Academic Journals: Coronavirus, May 6, 2020
Reviews, Commentary, and Miscellaneous
- Practical experiences on the prevention and treatment strategies to fight against COVID-19 in hospital Oxford Academic Journals: Coronavirus, May 5, 2020
- The COVID-19 pandemic: a live class on medical professionalism Oxford Academic Journals: Coronavirus, May 5, 2020
- Reply: Practical experiences on the prevention and treatment strategies to fight against COVID-19 in hospital Oxford Academic Journals: Coronavirus, May 5, 2020
- Coronavirus and the Navajo Nation New England Journal of Medicine: Coronavirus, May 5, 2020
- Text and Network-Mining for COVID-19 Intervention Studies ChemRxiv (Covid), May 5, 2020
Drug Development
- In Silico Screening of Naturally Occurring Coumarin Derivatives for the Inhibition of the Main Protease of SARS-CoV-2 ChemRxiv (Covid), May 5, 2020
- Screening and Druggability Analysis of Some Plant Metabolites Against SARS-CoV-2 ChemRxiv (Covid), May 5, 2020
- Computational Molecular Docking and Virtual Screening Revealed Promising SARS-CoV-2 Drugs ChemRxiv (Covid), May 6, 2020
- Sacubitril/valsartan in COVID-19 patients: the need for trials Oxford Academic Journals: Coronavirus, May 5, 2020
Newly Registered Clinical Trials
- COVID-19 Serology Screening and Strict Protocol in the Endoscopy Unit May 5, 2020
- Predicting Death and ICU Admission in COVID-19 Patients in ED May 5, 2020
- A Phase II, Open Label, Randomized Controlled Trial to Assess the Safety and Efficacy of Convalescent Plasma to Limit COVID-19 Associated Complications May 5, 2020
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BASIC SCIENCE AND EPIDEMIOLOGY
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Modeling and Prediction
- Is this the beginning or the end of COVID-19 outbreak in India? A data driven mathematical model-based analysis MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Dataset on the COVID-19 Pandemic Situation in Tunisia with application to SIR Model MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Novel indicator of change in COVID-19 spread status MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Brazilian Modeling of COVID-19 (BRAM-COD): a Bayesian Monte Carlo approach for COVID-19 spread in a limited data set context Outbreak Science, May 6, 2020
Public Health Intervention
- Investigating duration and intensity of Covid-19 social-distancing strategies MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Estimates of the ongoing need for social distancing and control measures post-"lockdown" from trajectories of COVID-19 cases and mortality. MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
Surveillance and sero-epidemiology
- CDC Urges COVID-19 Testing at Homeless Shelters after Finding Swift Spread of Infection JAMA Network: Coronavirus, May 5, 2020
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Coronavirus Research Resources
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China
- US couple’s nightmare: Held in China, away from daughter AP Health News: Coronavirus, May 5, 2020
- EU Aims to Counter Chinese, Russian Influence at Balkan Summit New York Times: Coronavirus, May 5, 2020
South Korea
- Baseball resumes in South Korea, bringing innings to a world starved for sports Washington Post: Coronavirus, May 5, 2020
- Baseball returned, live from South Korea, with a socially distant first pitch and bat flip Washington Post: Coronavirus, May 5, 2020
Italy
- U.K. Surpasses Italy In Recorded Coronavirus Deaths, Now Leads Europe In Fatalities NPR: Health, May 5, 2020
- Italy Expects at Least 100 Billion Euros From EU Recovery Fund New York Times: Coronavirus, May 5, 2020
- SPERLONGA, Italy (AP) — Normally at this time of year, the Italian seaside beach town of Sperlonga would have been bustling with its first clients of the season. AP Health News: Coronavirus, May 6, 2020
- EU Sees Italy Debt Ballooning to Nearly 160% This Year Amid Coronavirus Crisis New York Times: Coronavirus, May 6, 2020
Spain
- BRUSSELS (AP) — The three biggest races in cycling will take place in a 72-day span, starting with the Tour de France at the end of August and finishing with the Spanish Vuelta in... AP Health News: Coronavirus, May 5, 2020
- MADRID (AP) — Players and coaches at Spanish soccer club Eibar are deeply worried about playing again amid the coronavirus pandemic. A day after the Spanish league said teams can start... AP Health News: Coronavirus, May 5, 2020
France
- French Doctors Find COVID Case From December — A Month Before 1st Known Case There NPR: Health, May 5, 2020
- BRUSSELS (AP) — The three biggest races in cycling will take place in a 72-day span, starting with the Tour de France at the end of August and finishing with the Spanish Vuelta in... AP Health News: Coronavirus, May 5, 2020
- French doctors say they found a Covid-19 patient from December CNN.com - Health, May 5, 2020
- LONDON (AP) — French scientists say they may have identified a possible case of the new coronavirus dating back to December — about a month before the first cases were officially confirmed in... AP Health News: Coronavirus, May 5, 2020
- UNITED NATIONS (AP) — France and Tunisia urged the U.N. Security Council on Tuesday to adopt a resolution demanding an immediate cease-fire in major conflicts to tackle the coronavirus pandemic... AP Health News: Coronavirus, May 6, 2020
United Kingdom
- Britain on Tuesday became the first country in Europe to confirm more than 30,000 coronavirus deaths, and infections rose sharply again in Russia, even as other nations made great strides in... AP Health News: Coronavirus, May 5, 2020
- LONDON (AP) — Britain on Tuesday became the first country in Europe to confirm more than 30,000 coronavirus deaths, and infections rose sharply again in Russia, even as other nations made great... AP Health News: Coronavirus, May 5, 2020
- LONDON (AP) — After a delay caused by the coronavirus pandemic, British and American negotiators have opened negotiations on a trade agreement that the U.K. government hopes will bring a... AP Health News: Coronavirus, May 5, 2020
- Special Report: In Shielding Its Hospitals From COVID-19, Britain Left Many of the Weakest Exposed New York Times: Coronavirus, May 5, 2020
- One Ancient Mill Rises as Britain Bakes at Home New York Times: Coronavirus, May 6, 2020
Other International News
- Is this the beginning or the end of COVID-19 outbreak in India? A data driven mathematical model-based analysis MedRxiv Server for Health Sciences: Coronavirus, May 5, 2020
- Northeastern Brazil city is nation’s first to enter lockdown AP Health News: Coronavirus, May 5, 2020
- Britain on Tuesday became the first country in Europe to confirm more than 30,000 coronavirus deaths, and infections rose sharply again in Russia, even as other nations made great strides in... AP Health News: Coronavirus, May 5, 2020
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Government
- What to Know About Liver Disease and COVID-19 CDC: Coronavirus Disease: What's New, May 5, 2020
- WHO supports scientifically-proven traditional medicine WHO: Coronavirus disease (COVID-19) news, May 5, 2020
- Cruise Ship Crew Member Disembarkations CDC: Coronavirus Disease: What's New, May 6, 2020
- Employees: How to Cope with Job Stress and Build Resilience During the COVID-19 Pandemic CDC: Coronavirus Disease: What's New, May 6, 2020
- Healthcare Personnel and First Responders: How to Cope with Stress and Build Resilience During the COVID-19 Pandemic CDC: Coronavirus Disease: What's New, May 6, 2020
- Factors to Consider When Planning to Purchase Respirators from Another Country CDC: Coronavirus Disease: What's New, May 6, 2020
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Business and Economic News
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Business News
- California Sues Uber and Lyft to Classify Drivers as Employees Wired.com, May 5, 2020
- Adult Cam Site CAM4 Exposed 10.88 Billion Records Online Wired.com, May 5, 2020
- Best Amazon Devices Deals (May 2020): Kindles, Fire Tablets, Echo Speakers Wired.com, May 5, 2020
Economics Blogs
- COVID-19 & the Economy: A Q&A Session Greg Mankiw Blog, May 5, 2020
- U.S. Consumer Debt Payments and Credit Buffers on the Eve of COVID-19 Liberty Street Economics, May 5, 2020
- The impact of COVID-19 restrictions on individual mobility Bruegel: Blog, May 5, 2020
Top Economics News
- Biden's edge evaporates as Trump seen as better suited for economy, coronavirus response, poll shows US Economy (Reuters), May 5, 2020
- White House to wind down coronavirus task force as focus shifts to aftermath: Trump US Economy (Reuters), May 5, 2020
- U.S. trade deficit widens, services sector contracts amid coronavirus US Economy (Reuters), May 5, 2020
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Law Technology
- This Thursday: LawNext Live With An All-Star Panel On Law Firm Innovation In The Midst Of COVID-19 Robert Ambrogi's LawSites, May 5, 2020
- Coronavirus threat to global Good Growth Opportunities in E-Discovery Market - Cole of Duty (eDiscovery), May 5, 2020
- Judicial Conference Asks for More Money and Judges Due to Expected COVID-19 Backlog Blog of Legal Times, May 5, 2020
Legal Administrator
- This Thursday: LawNext Live With An All-Star Panel On Law Firm Innovation In The Midst Of COVID-19 Law Sites Blog, May 5, 2020
- Judicial Conference Asks for More Money and Judges Due to Expected COVID-19 Backlog Blog of Legal Times, May 5, 2020
- Wills In The Age Of COVID-19 TaxProf Blog, May 5, 2020
Librarian News
- This Thursday: LawNext Live With An All-Star Panel On Law Firm Innovation In The Midst Of COVID-19 Robert Ambrogi's LawSites, May 5, 2020
- UK Barristers will get help for priority Covid testing House of Butter, May 5, 2020
- UK: Thinktank warns of mission-creep in Coronavirus Act House of Butter, May 5, 2020
Leading Law Departments
- 5 Key Takeaways to Leverage Managed Contract Services in a COVID-19 Environment (via Passle) Elevate Services Blog, May 5, 2020
- How In-House Legal Teams Can Win with Tighter Budgets During COVID-19 (Adv.) Inhouse Blog, May 5, 2020
- Staff Issues FAQs on Covid-19 Relief CorporateCounsel.net Blog, May 5, 2020
- Keeping Business in Motion During COVID-19 Inside Counsel, May 5, 2020
- Do Workers Face Covid Risk From The New Joint Employer Ruling? Today's General Counsel: Career, May 5, 2020
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 | | Robert Morris, M.D., Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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