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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
3,992,967 |
274,985 |
| US |
1,314,295 |
78,248 |
Data from worldmeters.info
How to End the Lockdown: Pooled Workplace Testing and Customer Contact Tracing As epidemic curves fall in response to the strict lockdowns, the new challenge facing government agencies here in Washington, around the country, and around the world is getting people safely back to work. Testing will, of course, play a key role in doing that, but the lack of adequate testing supplies has constrained our ability to act. Pooled workplace testing can provide a strategy for early identification of cases with automatic contact tracing and limited resources.
Research News
SARS-CoV-2 testing results from New York State* suggest that secondary attack rates among household members of those diagnosed during March were 38%, far higher than those found in earlier studies. Prevalence among among all members of those house households range from 23% for children<5 to 68% among those >64 years of age.
A CDC survey of COVID-19 in 420 prisons found 2,778 cases and 15 deaths among staff and 4,893 cases with 88 deaths among prisoners. Case fatality rates were 1% among staff and 2% among prisoners.
An analysis of the impact of long term air pollution levels** on COVID-19 mortality and case fatality rates found that annual average nitrogen dioxide levels were consistently associated with both outcome measures independent of ozone or fine particulates.
An Israeli study** demonstrated the use of sample pooling, using 731 RT-PCR tests to identify six cases in a population of 5,464 people, 87% less than would be required for individual testing.
A study of the impact of blanket reopening strategies for US states** observes that the current delays between infection acquisition and case confirmation, including delays in obtaining test results, coupled with insufficient broader testing and contact tracing will mask any rebound in COVID-19 until exponential growth is well underway.
A French survey to assess the mental health impact** of the pandemic found that students, females, and the disabled tended to have the greatest reduction in mental wellbeing, while being employed, having more social contacts, and having access to the outdoors tended to improve wellbeing.
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*Prepublication **Not peer reviewed.
Covid19- Ahead of the Curve.
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Top News
- COVID-19 Testing, Epidemic Features, Hospital Outcomes, and Household Prevalence, New York State—March 2020 Oxford Academic Journals: Coronavirus, May 8, 2020
- EARLY RELEASE: COVID-19 in Correctional and Detention Facilities --- United States, February--April 2020 CDC: Morbidity and Mortality Weekly Report, May 7, 2020
- Urban Air Pollution May Enhance COVID-19 Case-Fatality and Mortality Rates in the United States MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- Large-scale implementation of pooled RNA-extraction and RT-PCR for SARS-CoV-2 detection MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- Projection of COVID-19 Cases and Deaths in the US as Individual States Re-open May 4,2020 MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- Who maintains a good mental health in a locked-down country? A French nationwide online survey of 11,391 participants MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
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Clinical Laboratory and Diagnostics
- Development and validation of direct RT-LAMP for SARS-CoV-2 MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- SARS-CoV-2 On-the-Spot Virus Detection Directly From Patients MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- A Peptide-based Magnetic Chemiluminescence Enzyme Immunoassay for Serological Diagnosis of Coronavirus Disease 2019 (COVID-19) Oxford Academic Journals: Coronavirus, May 8, 2020
Infection Control
- Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivity MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
Clinical Case Management
- Personalized Predictive Models for Symptomatic COVID-19 Patients Using Basic Preconditions: Hospitalizations, Mortality, and the Need for an ICU or Ventilator MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
Clinical Course and Outcomes
- Anti-TNF-α Agents in Inflammatory Bowel Disease and Course of COVID-19 Oxford Academic Journals: Coronavirus, May 8, 2020
- Initial COVID-19 affecting cardiac patients in China Oxford Academic Journals: Coronavirus, May 7, 2020
- COVID-19 in a 26-week preterm neonate Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
Impact on Other Specialties
- In Reply: The Coronavirus Disease 2019 Global Pandemic: A Neurosurgical Treatment Algorithm Oxford Academic Journals: Coronavirus, May 8, 2020
- Letter to the Editor: “Our Response to COVID-19 as Endocrinologists and Diabetologists” Oxford Academic Journals: Coronavirus, May 8, 2020
- Bariatric and metabolic surgery during and after the COVID-19 pandemic: DSS recommendations for management of surgical candidates and postoperative patients and prioritisation of access to surgery Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
Reviews, Commentary, and Miscellaneous
- Public health perspectives of smokeless tobacco and areca nut use in the COVID-19 era Oxford Academic Journals: Coronavirus, May 8, 2020
- Will COVID-19 fiscal recovery packages accelerate or retard progress on climate change? Oxford Academic Journals: Coronavirus, May 8, 2020
- Improving Detection and Response to Respiratory Events --- Kenya, April 2016--April 2020 CDC: Morbidity and Mortality Weekly Report, May 7, 2020
Mental Health
- COVID-19, healthcare workers and future mental health issues Oxford Academic Journals: Coronavirus, May 7, 2020
Drug Development
- Assessment of Hydroxychloroquine and Chloroquine Safety Profiles: A Systematic Review and Meta-Analysis MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
- Observational Study of Hydroxychloroquine in Covid-19 New England Journal of Medicine: Coronavirus, May 7, 2020
- Potential Drug Candidates for SARS-CoV-2 Using Computational Screening and Enhanced Sampling Methods ChemRxiv (Covid), May 7, 2020
Newly Registered Clinical Trials
- Risks of COVID19 in the Pregnant Population May 7, 2020
- COvid-19 National Survey for Assessing VIral Spread by Nonaffected CarriErs (CON-VINCE) May 7, 2020
- Neurologic Manifestations of COVID 19 in Children May 7, 2020
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BASIC SCIENCE AND EPIDEMIOLOGY
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Virology, Immunology, and Pathophysiology
- Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease 2019 JAMA Network: Coronavirus, May 7, 2020
- Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
- Assessment of SARS-CoV-2 replication in the context of other respiratory viruses Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
- Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Lancet: COVID-19 Resource Centre (Covid), May 8, 2020
- T cell subset counts in peripheral blood can be used as discriminatory biomarkers for diagnosis and severity prediction of COVID-19 Oxford Academic Journals: Coronavirus, May 7, 2020
Epidemiology
- SARS-CoV-2 transmission in different settings: Analysis of cases and close contacts from the Tablighi cluster in Brunei Darussalam MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
- Linear regression analysis of COVID-19 outbreak and control in Henan province caused by the output population from Wuhan MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
- Temperature and relative humidity are not major contributing factor on the occurrence of COVID-19 pandemic: An observational study in 57 countries MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
- The disproportionate rise in COVID-19 cases among Hispanic/Latinx in disadvantaged communities of Orange County, California: A socioeconomic case-series MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- The nexus of travel restriction, air pollution and COVID-19 infection: Investigation from a megacity of the southern China MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- Assessing COVID-19 Risk, Vulnerability and Infection Prevalence in Communities MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
Modeling and Prediction
- Forecasting COVID-19 new cases in Algeria using Autoregressive fractionally integrated moving average Models (ARFIMA) MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
- COVID-19 DYNAMICS: A HETEROGENEOUS MODEL MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- Impact of complete lock-down on total infection and death rates: A hierarchical cluster analysis MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
- On the estimation of the total number of SARS-CoV-2 infections MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- COVID-19 Scenarios: an interactive tool to explore the spread and associated morbidity and mortality of SARS-CoV-2 MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
Public Health Intervention
- COVID-19 spreading in Rio de Janeiro, Brazil: do the policies of social isolation really work? MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- New Zealand eliminates COVID-19 Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
- Chile plans controversial COVID-19 certificates Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
- COVID-19 in Brazil: “So what?” Lancet: COVID-19 Resource Centre (Covid), May 7, 2020
- Suppressing the impact of the COVID-19 pandemic using controlled testing and isolation MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
Surveillance and sero-epidemiology
- FIRST DETECTION OF SARS-COV-2 IN UNTREATED WASTEWATERS IN ITALY MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
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Coronavirus Research Resources
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China
- SEOUL, South Korea (AP) — China and South Korea both reported more coronavirus infections Friday after reopening economies damaged by devastating outbreaks. Around the globe, governments are... AP Health News: Coronavirus, May 8, 2020
- The Murdoch media’s China coronavirus conspiracy has one aim: get Trump re-elected | Kevin Rudd The Guardian (U.K.) - Opinions: Coronavirus, May 8, 2020
- China's New Yuan Loans Expected to Fall in April but Well Up From Year Earlier: Reuters Poll New York Times: Coronavirus, May 8, 2020
South Korea
- SEOUL, South Korea (AP) — China and South Korea both reported more coronavirus infections Friday after reopening economies damaged by devastating outbreaks. Around the globe, governments are... AP Health News: Coronavirus, May 8, 2020
Italy
- FIRST DETECTION OF SARS-COV-2 IN UNTREATED WASTEWATERS IN ITALY MedRxiv Server for Health Sciences: Coronavirus, May 7, 2020
- Women demand voice in Italy virus response dominated by men AP Health News: Coronavirus, May 7, 2020
- Italy to Inject 3 Billion Euros in New Alitalia: Industry Minister New York Times: Coronavirus, May 7, 2020
Germany
- German churches stopped singing to prevent virus’s spread. Should Americans clam up, too? Washington Post: Coronavirus, May 7, 2020
France
- Who maintains a good mental health in a locked-down country? A French nationwide online survey of 11,391 participants MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
United Kingdom
- LONDON (AP) — Almost all ethnic minorities in Britain are at greater risk of dying with the coronavirus, and black men and black women are nearly twice as likely to die than white individuals,... AP Health News: Coronavirus, May 7, 2020
- LONDON (AP) — A new work by the elusive street artist Banksy, honoring health workers, has been unveiled at a British hospital. The framed picture, titled “Game Changer,” depicts a young boy... AP Health News: Coronavirus, May 7, 2020
- Easing British Lockdown Is 'Point of Maximum Risk': Raab New York Times: Coronavirus, May 7, 2020
- Blacks in Britain are four times as likely to die of coronavirus as whites, data show Washington Post: Coronavirus, May 7, 2020
- LONDON (AP) — Britain was expected to extend its nationwide lockdown on Thursday, but the European country hit hardest by the coronavirus plans cautiously to ease some restrictions on economic and... AP Health News: Coronavirus, May 7, 2020
Other International News
- Clinical characteristics of patients with COVID-19 in Japan: a single-center case series Infectious Diseases Society of America Journals: Coronavirus, May 8, 2020
- Indonesia Reports 336 Coronavirus Infections, 13 Deaths New York Times: Coronavirus, May 8, 2020
- Sony to Make, Donate Face Shields to Japan Hospitals New York Times: Coronavirus, May 8, 2020
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Government
- Arriving Passengers Health Card CDC: Coronavirus Disease: What's New, May 8, 2020
- Guidance for Cleaning and Disinfecting CDC: Coronavirus Disease: What's New, May 7, 2020
- What Workers and Employers Can Do to Manage Workplace Fatigue during COVID-19 CDC: Coronavirus Disease: What's New, May 7, 2020
- COVID-19 Critical Infrastructure Sector Response Planning CDC: Coronavirus Disease: What's New, May 7, 2020
- Pets and Other Animals CDC: Coronavirus Disease: What's New, May 7, 2020
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Business and Economic News
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Business News
- California was one of the first states to issue a stay-at-home order. Tomorrow, it'll start to reopen CNN.com - Health, May 8, 2020
- Will COVID-19 fiscal recovery packages accelerate or retard progress on climate change? Oxford Academic Journals: Coronavirus, May 8, 2020
- Suppressing the impact of the COVID-19 pandemic using controlled testing and isolation MedRxiv Server for Health Sciences: Coronavirus, May 8, 2020
Economics Blogs
- The potential impact of the COVID-19 on child abuse and neglect VoxEU.org, May 8, 2020
- COVID-19 will raise inequality if past pandemics are a guide VoxEU.org, May 8, 2020
- Political participation, populism, and the COVID-19 Crisis VoxEU.org, May 8, 2020
Top Economics News
- Brazils economy faces collapse over coronavirus lockdown: Paulo Guedes - Geo News (Brazilian Economy), May 8, 2020
- Ohio to reopen bars, restaurants in 2 weeks | Coronavirus - Meadville Tribune (Brazilian Economy), May 8, 2020
- Fuelling change: how covid-19 is impacting Brazil's oil industry - Latin Lawyer (Brazilian Economy), May 8, 2020
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Law Technology
- How Indian insurance companies can respond to coronavirus McKinsey Insights & Publications, May 8, 2020
- Rapid Revenue Recovery: A road map for post-COVID-19 growth McKinsey Insights & Publications, May 8, 2020
- How COVID-19 is reshaping China’s medtech industry McKinsey Insights & Publications, May 8, 2020
Legal Administrator
- Spring Hiring Trends in the COVID-19 Era EntertainHR, May 8, 2020
- Lux & Law Firm Partners - So Pre-COVID-19 Law and More, May 8, 2020
- "Mark Kanyuk v. Shearman & Sterling" - Age Discrimination Lawsuit in The Year of COVID-19 Law and More, May 7, 2020
Librarian News
- The First 100 Days of the U.S. Government’s COVID-19 Response beSpacific, May 8, 2020
- UC Hastings Dean: After COVID-19 a 'Simmering Problem' in SF's Tenderloin Neighborhood 'Has Boiled Over' law.com: Newswire, May 8, 2020
- Higher Law: UCANN Files for Bankruptcy | A Cannabis COVID-19 Playbook | Feuerstein Kulick Adds a Cannabis Financier | A Successful Bid for Coronavirus Aid law.com: Newswire, May 8, 2020
Leading Law Departments
- Own Your Career – Don’t Let It Be a Covid Casualty Inhouse Blog, May 7, 2020
- Keeping Business in Motion During COVID-19 Epiq Systems, May 7, 2020
- The Effect of COVID-19 on Disputes and Investigations (via Passle) Elevate Services Blog, May 7, 2020
- Virtual Summit Poll Results: How Has Coronavirus Impacted Legal Ops? Mitratech: Press Releases, May 7, 2020
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 | | Robert Morris, MD, PhD, Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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