|
COVID-19 Report
 |
|
|
 The Count
| Region |
Cases |
Deaths |
| World |
5,150,770 |
332,242 |
| US |
1,604,843 |
95,656 |
Research News
SUMMARY
- A model of county level COVID-19 deaths and reported cases in the US found that population density, poverty, and minority populations, especially African Americans, were associated with increased risk, while social distancing decreased risk. This has major implications for both predicting spread and targeting interventions to reduce inequity in the impact of the disease.
- A study of SARS-CoV-2 seroconversion in Asymptomatic health care workers (HCWs) found that 24.4% of HCWs in a tertiary care hospital had antibodies, 37.5% in those with symptoms and 17.1% in those without. Antibody levels are significantly higher among those who are asymptomatic.
- A study of seroconversion rates among SARS-CoV-2 positive hospital patients in France found that 57% of asymptomatic carriers did not develop antibodies and those that did become antibody positive had lower antibody levels than patients with symptomatic disease. This raises questions about the level of immunity conferred by antibodies in asymptomatic carriers.
- A Japanese study of salivary testing supports its use as an alternative to nasopharyngeal swabs for detection of the SARS-CoV-2 virus. This has the potentially to dramatically increase the ease of testing and to reduce the risk to healthcare workers related to sample collection.
- Evidence of immunosuppression by SARS-CoV-2 was found in a study of innate immune response to the virus. Reduced indicators included expression of genes involved in toll-like receptor and interleukin signaling, chemokine binding, neutrophil degranulation and interactions with lymphoid cells as well as proportions of neutrophils and macrophages. These findings suggest that the virus specifically targets cellular immunity to reduce the host's capacity to fight infections.
- The nature of the T-cell response was linked to the development of severe symptoms from COVID-19 in a study that found a stronger response of S-protein specific T-cells producing inflammatory cytokines was associated with more severe disease. This may provide a marker to predict for severe disease and a possible approach to treatment.
- Antibodies from selected and cloned B-cells blocked entry of SARS-CoV-2 into human cells in vitro, suggesting the potential for a treatment option based on monoclonal antibodies.
- The area of visceral adipose tissue demonstrated a strong association with the risk of ICU treatment in a German study. This could be an important tool for predicting risk and managing patients.
- SARS-CoV-2 RNA was found in environmental samples near a hospital in Wuhan. Soil, air, and water at specific locations around the hospital were contaminated, which suggests a need for extra steps to prevent spread through the environment in these areas.
* * * * *
*Preprint **Not peer reviewed.
- Covid19- Ahead of the Curve.
* * * * *
|
|
|
| |
|
|
|
Clinical Laboratory and Diagnostics
- Covid-19 Detection using CNN Transfer Learning from X-ray Images MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- A collaborative online AI engine for CT-based COVID-19 diagnosis MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Emergency Care and Triage
- Novel coronavirus COVID-19: an overview for emergency clinicians. NIH: National Library of Medicine: Coronavirus, May 19, 2020
- Covid-19 Crisis Triage New England Journal of Medicine: Coronavirus, May 19, 2020
- Need for Transparency and Reliable Evidence in Emergency Use Authorizations for Coronavirus Disease 2019 (COVID-19) Therapies JAMA Network: Coronavirus, May 19, 2020
Infection Control
- COVID-19 management in a UK NHS Foundation Trust with a High Consequence Infectious Diseases centre: a detailed descriptive analysis MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Prevention of COVID-19 in patients with IBD Lancet: COVID-19 Resource Centre (Covid), May 19, 2020
- Protecting patients with IBD during the COVID-19 pandemic Lancet: COVID-19 Resource Centre (Covid), May 19, 2020
Clinical Case Management
- EFFECTS OF COVID-19 INFECTION DURING PREGNANCY AND NEONATAL PROGNOSIS: WHAT IS THE EVIDENCE? MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Safe and effective management of tracheostomy in COVID‐19 patients Wiley: Coronavirus Research & News, May 20, 2020
- 4 Cases: HIV and SARS‐CoV‐2 Co‐infection in patients from Long Island, New York Wiley: Coronavirus Research & News, May 20, 2020
- Starting a biologic therapy in IBD patients amidst COVID-19: hold, careful monitoring or testing? Oxford Academic Journals: Coronavirus, May 19, 2020
- Septic shock presentation in adolescents with COVID-19 Lancet: COVID-19 Resource Centre (Covid), May 19, 2020
- Empirical Assessment of COVID-19 Crisis Standards of Care Guidelines MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
ICU Care
- VENTILATORY SUPPORT IN SARS-VOC-2 DURING INTENSIVE THERAPY MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Clinical Course and Outcomes
- COVID‐19 complicated by acute myocardial infarction with extensive thrombus burden and cardiogenic shock Wiley: Coronavirus Research & News, May 20, 2020
- Case report of anterior ST-elevation myocardial infarction in a patient with coronavirus disease-2019 Oxford Academic Journals: Coronavirus, May 19, 2020
- Famotidine Use is Associated with Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Propensity Score Matched Retrospective Cohort Study MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Impact on Other Specialties
- Estimation of the number of general anesthesia cases based on a series of nationwide surveys on Twitter during COVID-19 in Japan: A statistical analysis MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Mental health, physical activity and quality of life in Parkinson's disease during COVID‐19 pandemic Wiley: Coronavirus Research & News, May 20, 2020
- Staying ahead of the curve: Early lessons from a New York City Otolaryngology Department's organizational response to the coronavirus pandemic Wiley: Coronavirus Research & News, May 20, 2020
Reviews, Commentary, and Miscellaneous
- Moving Beyond a Peak Mentality: Plateaus, Shoulders, Oscillations and Other 'Anomalous' Behavior-Driven Shapes in COVID-19 Outbreaks MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Disrupt, Innovate, and Transform in the Era of COVID‐19 Wiley: Coronavirus Research & News, May 20, 2020
- Love in the time of COVID‐19 Wiley: Coronavirus Research & News, May 20, 2020
Mental Health
- Mental Health Status of the General Population during the COVID-19 Pandemic: A Cross-sectional National Survey in Japan MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Is it Just About Physical Health? An Internet-Based Cross-Sectional Study Exploring the Psychological Impacts of COVID-19 Pandemic on University Students in Jordan Using Kessler Psychological Distress Scale MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- How are adversities during COVID-19 affecting mental health? Differential associations for worries and experiences and implications for policy MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- COVID-19 Worries and Behavior Changes in Older and Younger Men and Women Oxford Academic Journals: Coronavirus, May 19, 2020
- Mental health in the UK during the COVID-19 pandemic: early observations MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Drug Development
- Repurposing the Natural Compound for Antiviral During an Epidemic -a Case Study on the Drug Repurpose of Natural Compounds to Treat COVID-19 ChemRxiv (Covid), May 20, 2020
- Drug Repurposing for COVID-19 from FDA Approved and Experiment Stage Drugs by in Silico Methods with SARS CoV-2 Spike Protein ChemRxiv (Covid), May 20, 2020
- In Silico Investigation of Spice Molecules as Potent Inhibitor of SARS-CoV-2 ChemRxiv (Covid), May 20, 2020
Newly Registered Clinical Trials
- Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care (LUS-COVID19) May 19, 2020
- Efficacy of Ivermectin in COVID-19 May 19, 2020
- Do Vitamin D Levels Really Correlated With Disease Severity in COVID-19 Patients? May 19, 2020
|
|
|
| |
|
BASIC SCIENCE AND EPIDEMIOLOGY
|
|
Virology, Immunology, and Pathophysiology
- Transcriptional profiling of immune and inflammatory responses in the context of SARS-CoV-2 fungal superinfection in a human airway epithelial model bioRxiv: The Preprint Server for Biology (Covid), May 20, 2020
- Deep phylogenetic analysis of bioRxiv: The Preprint Server for Biology (Covid), May 19, 2020
- Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication bioRxiv: The Preprint Server for Biology (Covid), May 19, 2020
Vaccine Development
- Multi-Antigenic Virus-like Particle of SARS CoV-2 produced in Saccharomyces cerevisiae as a vaccine candidate bioRxiv: The Preprint Server for Biology (Covid), May 20, 2020
- [Strategies for vaccine development of COVID-19]. NIH: National Library of Medicine: Coronavirus, May 19, 2020
Epidemiology
- Estimative of real number of infections by COVID-19 on Brazil and possible scenarios MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Estimation of COVID-19 spread curves integrating global data and borrowing information MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Manifestations of mortality based global data of COVID-19; unifying global model through single parameter MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Modeling and Prediction
- A dynamic model for Covid-19 in Brazil. MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Reciprocal association between participation to a national election and the epidemic spread of COVID-19 in France: nationwide observational and dynamic modeling study. MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Potential Non-Covalent SARS-CoV-2 3C-like Protease Inhibitors Designed Using Generative Deep Learning Approaches and Reviewed by Human Medicinal Chemist in Virtual Reality ChemRxiv (Covid), May 19, 2020
Public Health Intervention
- Can we use these masks? Rapid Assessment of the Inhalation Resistance Performance of Uncertified Medical Face Masks in the Context of Restricted Resources Imposed during a Public Health Emergency MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Personal Protective Equipment and Covid-19 New England Journal of Medicine: Coronavirus, May 19, 2020
- Responding to COVID-19: The experience from Italy and recommendations for management and prevention Oxford Academic Journals: Coronavirus, May 19, 2020
Surveillance and sero-epidemiology
- The infection fatality rate of COVID-19 inferred from seroprevalence data MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19 Oxford Academic Journals: Coronavirus, May 19, 2020
|
|
|
| |
Coronavirus Research Resources
|
|
|
| |
|
National News
- All states will be partially reopened by Wednesday despite at least 17 seeing coronavirus case rates rise CNN.com - Health, May 20, 2020
- ISTANBUL (AP) — They see themselves as public health detectives, working 24/7 to track the coronavirus' insidious spread through a country of 83 million, blending door-to-door hoof work with... AP Health News: Coronavirus, May 20, 2020
- HOOVER, Ala. (AP) — High schools nationwide have canceled or postponed traditional graduation ceremonies to avoid worsening the spread of the new coronavirus, but some are going ahead with... AP Health News: Coronavirus, May 20, 2020
|
|
|
| |
|
China
- BEIJING (AP) — When China convenes its National People's Congress on Friday, will the 3,000 delegates stand shoulder to shoulder? Will they wear masks? AP Health News: Coronavirus, May 20, 2020
- TAIPEI, Taiwan (AP) — Taiwanese President Tsai Ing-wen called for stability in relations with China in her inaugural address Wednesday but said she would not accept Beijing’s political terms that... AP Health News: Coronavirus, May 20, 2020
- US, China standoff ensnares WHO meeting on COVID-19 fight AP Health News: Coronavirus, May 19, 2020
- China Reports Five New COVID-19 Cases for May 19 vs 6 Day Earlier New York Times: Coronavirus, May 19, 2020
- Clinical characteristics of patients infected with the novel 2019 coronavirus (SARS-Cov-2) in Guangzhou, China Oxford Academic Journals: Coronavirus, May 19, 2020
- Changing travel patterns in China during the early stages of the COVID-19 pandemic MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
South Korea
- BANGKOK (AP) — Hundreds of thousands of high school seniors in South Korea had their temperature checked and rubbed their hands with sanitizer as they returned to school Wednesday, many for the... AP Health News: Coronavirus, May 20, 2020
- SEOUL, South Korea (AP) — South Korean students began returning to school on Wednesday, but not without some hitches. Hundreds of thousands of high school seniors entered their schools after... AP Health News: Coronavirus, May 20, 2020
- SEOUL, South Korea (AP) — South Korean students began returning to classes Wednesday even as the country counted another 32 new coronavirus cases. AP Health News: Coronavirus, May 20, 2020
- COVID-19 FATALITY RISK: WHY IS AUSTRALIA LOWER THAN SOUTH KOREA? MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Italy
- Responding to COVID-19: The experience from Italy and recommendations for management and prevention Oxford Academic Journals: Coronavirus, May 19, 2020
- Is there a link between temperatures and COVID-19 contagions? Evidence from Italy MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Mortality rates from COVID-19 in Spain and Italy, Lessons for the UK! MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Survival of hospitalized COVID-19 patients in Northern Italy: a population-based cohort study by the ITA-COVID19 Network MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Spain
- Mortality rates from COVID-19 in Spain and Italy, Lessons for the UK! MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
Germany
- Flatten the Curve! Modeling SARS-CoV-2/COVID-19 Growth in Germany on the County Level MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- The Clinical and Economic Value of a Successful Shutdown During the SARS-CoV-2 Pandemic in Germany MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Germany, France Propose $543 Billion EU Coronavirus Recovery Fund NPR: Health, May 19, 2020
France
- Reciprocal association between participation to a national election and the epidemic spread of COVID-19 in France: nationwide observational and dynamic modeling study. MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Monitoring and predicting SARS-CoV-2 epidemic in France after deconfinement using a multiscale age-stratified rate model MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- Germany, France Propose $543 Billion EU Coronavirus Recovery Fund NPR: Health, May 19, 2020
- LE PECQ, France (AP) — How’s this as an antidote for coronavirus blues: A genuine painting by Pablo Picasso on your wall. After an eight-week delay caused by France’s COVID-19 lockdown, the... AP Health News: Coronavirus, May 19, 2020
- Emmanuel Macron’s party loses absolute majority in French parliament Washington Post: Coronavirus, May 19, 2020
United Kingdom
- LEBANON, N.H. (AP) — Dartmouth-Hitchcock is creating a virtual center to improve treatment of Crohn's disease across northern New England. The health system will use a grant from the Leona... AP Health News: Coronavirus, May 19, 2020
- Diagnostic accuracy of Faecal Immunochemical Testing for patients with symptoms of colorectal cancer: a retrospective cohort study of 14,487 consecutive test requests from English primary care. MedRxiv Server for Health Sciences: Coronavirus, May 19, 2020
- LONDON (AP) — An influential group of British lawmakers on Tuesday accused Prime Minister Boris Johnson’s government of failing to conduct enough tests for the new coronavirus, saying the lapse... AP Health News: Coronavirus, May 19, 2020
Other International News
- Mental Health Status of the General Population during the COVID-19 Pandemic: A Cross-sectional National Survey in Japan MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Estimative of real number of infections by COVID-19 on Brazil and possible scenarios MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- Estimation of the number of general anesthesia cases based on a series of nationwide surveys on Twitter during COVID-19 in Japan: A statistical analysis MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
|
|
|
| |
|
|
| |
Business and Economic News
|
|
Business News
- All states will be partially reopened by Wednesday despite at least 17 seeing coronavirus case rates rise CNN.com - Health, May 20, 2020
- A collaborative online AI engine for CT-based COVID-19 diagnosis MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
- A one-year hospital-based prospective COVID-19 open-cohort in the Eastern Mediterranean region: The Khorshid COVID Cohort (KCC) study MedRxiv Server for Health Sciences: Coronavirus, May 20, 2020
Economics Blogs
- Accounting for global COVID-19 diffusion patterns VoxEU.org, May 20, 2020
- Covid-19 and the future of democracy VoxEU.org, May 20, 2020
- Post-COVID: Dealing with the emerging market debt overhang VoxEU.org, May 20, 2020
Top Economics News
- UPDATE 1-WTO's goods trade index hits record low amid COVID disruptions US Economy (Reuters), May 20, 2020
- Greek economy to shrink by up to 13% this year due to coronavirus-FinMin Greek Economy (Reuters), May 20, 2020
- Brazil suffers record coronavirus deaths, Trump mulls travel ban US Economy (Reuters), May 19, 2020
|
|
|
| |
|
|
| |
|
Law Technology
- A systems exploration of the COVID-19 crisis RealKM, May 20, 2020
- Event: COVID-19 Response Story Webinar, Wed 27 May 2020, Gurteen Knowledge, May 20, 2020
- Scaling rapid workforce conversion during COVID-19 McKinsey Insights & Publications, May 19, 2020
Legal Administrator
- HiPo Leadership Strategies to Get Balanced and Be on Target During the COVID-19 Crisis EntertainHR, May 20, 2020
- Biglaw Firm Enacts Voluntary Leave Amid COVID-19 Upheaval Above the Law - Big Law, May 19, 2020
- Coronavirus Craters Law Firm Revenues, With 81 Percent Of Surveyed Firms Seeing Losses Above the Law - Big Law, May 19, 2020
Librarian News
- Ashurst UK: The Coronavirus Job Retention Scheme: Q&As for employers House of Butter, May 20, 2020
- Price Gouging in California (and Elsewhere) During COVID-19 … And the Claims That Are Likely to Follow House of Butter, May 20, 2020
- CDC guidance on reopening America from coronavirus stay-at-home orders beSpacific, May 20, 2020
Leading Law Departments
- Webinar | COVID-19’s Impact on the H-1B Visa Process General Counsel News, May 19, 2020
- Akerman Launches Return to Work Resource Guide for Employers Following Shutdown Caused by COVID-19 Pandemic General Counsel News, May 19, 2020
- Part II: How Public Companies Can Minimize Risks Resulting From a Post-COVID-19 Focus on ESG Issues Inside Counsel, May 19, 2020
|
|
|
| |
 | | Robert Morris, MD, PhD, Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
The COVID-19 Daily Alert powered by PinHawk
Click here for your free newsletter subscription
Click here to read COVID-19, Notes from Seattle, Dr. Morris's daily blog
{NEWSLETTER_FORMAT_OPTION}
|
|
Copyright © 2020 by PinHawk LLC. All rights reserved.
PinHawk LLC does not warrant that the information in this email will meet any specific requirements nor that it will be error free or uninterrupted; nor shall PinHawk LLC be liable for any indirect, incidental or consequential damages (including lost data, information or profits) sustained or incurred in connection with the use of, operation of, or inability to use the information contained herein. By reading this email you agree to the Terms and Conditions.
Contact: PinHawk LLC, 445 Hamilton Avenue, Suite 1102, White Plains, NY 10601, tel. 914-358-0034 or comments@pinhawk.com
Don't let this important email be caught by a spam filter, ensure delivery to your inbox.
Comment / Tell a friend / Advertise / Unsubscribe
|
| | | | | | | | | |
| |
