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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
7,064,838 |
404,566 |
| US |
2,006,453 |
112,458 |
COVID Lives Matter As America takes to the streets to express its anger and frustration over the deaths of its black citizens, COVID-19 continues to kill. Cruelly, the pandemic appears to pick its victims based on the color of their skin..
Research News
SARS-CoV-2 Infections in New York City Tied to Indicators of Socioeconomic Status Researchers at Mt. Sinai Medical Center found that infection rates at the ZIP Code level was closely tied to household crowding, lack of Medical Insurance, low income, and unemployment. As an ecological study of ZIP code areas, the study is limited in its ability to draw inferences about individual risk, but it does describe the impact of neighborhoods. The mortality analysis adjusted for age using only the percent of the population above 65 years of age, a variable unlikely to fully account for the impact of age given its critical role in determining disease severity.
SARS-CoV-2 Infections in New York City Tied to Indicators of Socioeconomic Status Another study conducted by researchers from the Columbia business school found that household size, % below the poverty line, and %>65 were strong predictors of the rate of confirmed cases of COVID-19 in NYC ZIP code areas with household size being the dominant variable. Again, the adjustment for age seems inadequate, but it is highly likely that household crowding plays a critical role in spreading the disease
A Chinese Study Demonstrates the Benefits of Strict Adherence to Rules to Protect Public Health The study of public health measure in Wuhan emphasized the risks associated with not following public health measures, but the truly striking finding involved the degree to which those measures were followed. 37% of 8158 respondents to a public health survey never left home during the pandemic and, among those who did, 98% wore a mask. Out of all subjects, 99.2% agreed that the fight with COVID-19 was everyone's job.
Attitudes About Reopening Do Not Follow Party Lines 40% of Republicans and 44% of Democrats favored risk minimization strategies. 24% of Republicans and 20% of Democrats favored faster economic recovery to safety.
Saliva Samples May be Sufficient for Abbot Labs SAS-CoV-2 Samples Tests of saliva as a testing medium on 96 saliva samples with 64 nasopharyngeal samples (conventional sampling) found 78% positive agreement and 100% negative agreement. The saliva samples stayed positive even when stored at room temperature for five days.
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*Preprint **Not peer reviewed.
Covid19- Ahead of the Curve.
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Clinical Laboratory and Diagnostics
- Swab Tests and COVID 19, Italy case studied using Artificial Intelligence, Statistical Analysis and MLR MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Rapid detection of SARS-CoV-2 and other respiratory viruses by using LAMP method with Nanopore Flongle workflow bioRxiv: The Preprint Server for Biology (Covid), June 4, 2020
- Development and validation of chest CT-based imaging biomarkers for early stage COVID-19 screening MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Emergency Care and Triage
- A prediction model based on machine learning for diagnosing the early COVID-19 patients MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia - challenges, strengths, and opportunities in a global health emergency MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Sensitivity and specifity of prediction models based on gustatory disorders in diagnosing COVID-19 patients: a case-control study. MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Reduction in stroke patients' referral to the ED in the COVID-19 era: A four-year comparative study MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Development and Prospective Validation of a Transparent Deep Learning Algorithm for Predicting Need for Mechanical Ventilation MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Characterizing and Forecasting Emergency Department Visits Related to COVID-19 Using Chief Complaints and Discharge Diagnoses MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Infection Control
- The Effect of Ultraviolet C Radiation Against SARS-CoV-2 Inoculated N95 Respirators MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Repurposed prophylaxis strategies for COVID-19: a systematic review MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Safety Stock: Predicting demand on the supply chain in Brazilian hospitals during the COVID-19 pandemic MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Minimising exposure to droplet and aerosolised pathogens: a computational fluid dynamics study MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Clinical Case Management
- Rethinking antiviral effects for COVID-19 in clinical studies: early initiation is key to successful treatment MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Continuous positive airway pressure face-mask ventilation to manage massive influx of patients requiring respiratory support during the SARS-CoV-2 outbreak MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
ICU Care
- Estimating critical care capacity needs and gaps in Africa during the COVID-19 pandemic MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Tocilizumab for treatment of mechanically ventilated patients with COVID-19 MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Clinical Course and Outcomes
- Risk factors for mortality in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Statistical methods for estimating cure fraction of COVID-19 patients in India MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Clinical Features and Predictors for Patients with Severe SARS-CoV-2 Pneumonia: a retrospective multicenter cohort study MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Impact on Other Specialties
- How urgent do intravitreal anti-VEGF injections need to be to justify the risk of transmitting COVID-19? Proof-of-concept calculations to determine the Health Adjusted Life-Year (HALY) trade-off. MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
Reviews, Commentary, and Miscellaneous
- Knowledge and attitude towards COVID-19 in Bangladesh: Population-level estimation and a comparison of data obtained by phone and online survey methods MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Ischemic Stroke in COVID-19: An Urgent Need for Early Identification and Management MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Knowledge, attitude, and practice regarding COVID-19 outbreak in Bangladeshi people: An online-based cross-sectional study MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Mental Health
- Psychological Impact of COVID-19 on Pakistani University Students and How They Are Coping MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Are adversities and worries during the COVID-19 pandemic related to sleep quality? Longitudinal analyses of 45,000 UK adults MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Trajectories of depression and anxiety during enforced isolation due to COVID-19: longitudinal analyses of 59,318 adults in the UK with and without diagnosed mental illness MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- When "Shelter-in-Place" Isn't Shelter That's Safe: A Rapid Analysis of Domestic Violence Case Differences During the COVID-19 Pandemic and Stay-at-Home Orders MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Drug Development
- Missing clinical trial data: the knowledge gap in the safety of potential COVID-19 drugs MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- A SYSTEMATIC ANALYSIS OF THE TIME COURSE TO DEVELOP TREATMENTS FOR COVID-19 MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Inhibition of Corona virus spike protein binding to ACE2 bioRxiv: The Preprint Server for Biology (Covid), June 4, 2020
Newly Registered Clinical Trials
- USZ BioResource COVID June 4, 2020
- The Role of a Private Hospital in Hong Kong Amid COVID-19 Pandemic June 4, 2020
- COVID19 Clinical Predictors and Outcome June 4, 2020
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BASIC SCIENCE AND EPIDEMIOLOGY
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Virology, Immunology, and Pathophysiology
- Substitutions in Spike and Nucleocapsid proteins of SARS-CoV-2 circulating in Colombia MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Increased serum levels of sCD14 and sCD163 indicate a preponderant role for monocytes in COVID-19 immunopathology MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Assembly of an integrated human lung cell atlas reveals that SARS-CoV-2 receptor is co-expressed with key elements of the kinin-kallikrein, renin-angiotensin and coagulation systems in alveolar cells MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
Vaccine Development
- In silico design and characterization of multiepitopes vaccine for SARS-CoV from its Spike proteins bioRxiv: The Preprint Server for Biology (Covid), June 4, 2020
Epidemiology
- Globally Coherent Weekly Periodicity in the Covid-19 Pandemic MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Climatic influence on the magnitude of COVID-19 outbreak: a stochastic model-based global analysis MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Using viral genomics to estimate undetected infections and extent of superspreading events for COVID-19 MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Modeling and Prediction
- COVID-19: A model correlating BCG vaccination to protection from mortality implicates trained immunity MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Is India heading towards a new high? : An optimistic approach to estimate ending life-cycle and cumulative cases by the end of the major COVID-19 pandemic wave in India and some of its states. MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- A TRANSPARENT, OPEN-SOURCE SIRD MODEL FOR COVID19 DEATH PROJECTIONS IN INDIA MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
Public Health Intervention
- A hybrid multi-scale model of COVID-19 transmission dynamics to assess the potential of non-pharmaceutical interventions MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Evaluating reduction in CoViD-19 cases by isolation and protective measures in São Paulo State, Brazil, and scenarios of release MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- TAMING COVID-19 EPIDEMIC IN SÃO PAULO WITH A LOGISTIC MODEL AND NON-PHARMACEUTICAL MEASURES MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
Surveillance and sero-epidemiology
- Evaluating the adequacy of Prima Covid-19 IgG/IgM Rapid Test for the assessment of exposure to SARS-CoV-2 virus MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Evaluation of serological tests for SARS-CoV-2: Implications for serology testing in a low-prevalence setting MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Concordance of "rapid" serological tests and IgG and IgM chemiluminescence for SARS-COV-2 MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
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Coronavirus Research Resources
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China
- The Relationship Between COVID-19 Infection and Risk Perception, Knowledge, Attitude As Well As Four Non-pharmaceutical Interventions (NPIs) During the Late Period Of The COVID-19 Epidemic In China — An Online Cross-sectional Survey of 8158 Adults MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- The Chest CT Features of Coronavirus Disease 2019 (COVID-19) in China: A Meta-analysis of 19 Trials MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
- Epidemiological and Genomic Analysis of SARS-CoV-2 in Ten Patients from a Mid-sized City outside of Hubei, China in the Early Phase of the COVID-19 Outbreak MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Italy
- Swab Tests and COVID 19, Italy case studied using Artificial Intelligence, Statistical Analysis and MLR MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Using newspapers obituaries to nowcast daily mortality: evidence from the Italian COVID-19 hot-spots MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
Spain
- COVID-19 apparent reproductive number dropped during Spain's nationwide dropdown, then spiked at lower-incidence regions MedRxiv Server for Health Sciences: Coronavirus, June 3, 2020
France
- Early phylodynamics analysis of the COVID-19 epidemics in France MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
Other International News
- Is India heading towards a new high? : An optimistic approach to estimate ending life-cycle and cumulative cases by the end of the major COVID-19 pandemic wave in India and some of its states. MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- Evaluating reduction in CoViD-19 cases by isolation and protective measures in São Paulo State, Brazil, and scenarios of release MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
- A TRANSPARENT, OPEN-SOURCE SIRD MODEL FOR COVID19 DEATH PROJECTIONS IN INDIA MedRxiv Server for Health Sciences: Coronavirus, June 4, 2020
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Business and Economic News
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Business News
- As America Struggles To Return To Work, Staggering Unemployment Numbers Loom NPR: Health, June 5, 2020
- Farmers Find Ways To Save Millions Of Pigs From Slaughter NPR: Health, June 5, 2020
- Curfews Halt Transit Services—and Leave Riders Stranded Wired.com, June 4, 2020
Economics Blogs
- Flattening the COVID-19 curve: What works VoxEU.org, June 5, 2020
- The effect of containment measures on the COVID-19 pandemic VoxEU.org, June 5, 2020
- Accelerating development of a Covid-19 vaccine VoxEU.org, June 4, 2020
- Covid-19 and emerging economies: What to expect in the short- and medium-term Bruegel: Blog, June 4, 2020
- Millions Of Higher-Paying Jobs Targeted As Next Wave Of COVID Layoffs Begins Zero Hedge, June 3, 2020
- Data Rights and Data Protection during COVID-19 San Francisco Feds Blog, June 3, 2020
Top Economics News
- German Factory Orders Fall Most Since 1991 On Covid-19 RTT News: Asian Economic News, June 5, 2020
- Covid crisis likely to mask economic fallout of no-deal Brexit | Free to read - Financial Times (Brexit Economy News), June 5, 2020
- How Covid-19 Has Made Brexit Even Harder - Bloomberg (Brexit Economy News), June 5, 2020
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Law Technology
- Gartner's COVID-19 Report: Focus on These 7 Cybersecurity Risk Areas Exterro Blog, June 5, 2020
- Spain after COVID-19: From resilience to reimagination McKinsey Insights & Publications, June 5, 2020
- CFO leadership in the COVID-19 crisis McKinsey Insights & Publications, June 5, 2020
Legal Administrator
- Pennsylvania Employer Faces Lawsuit in State’s First COVID-19 Death Case EntertainHR, June 5, 2020
- Michael Graetz Saw The ‘Wolf At The Door’ Before The Coronavirus Arrived In The U.S. TaxProf Blog, June 4, 2020
- 5 Lessons to Help You Develop Business in a Post Covid-19 World Legal Marketing Blog, June 4, 2020
Librarian News
- AALL Webinar: LAW LIBRARIANS COMBATTING INFODEMIC DURING THE COVID-19 PANDEMIC House of Butter, June 5, 2020
- Emergency coronavirus appeal smashes £400,000 target House of Butter, June 5, 2020
- Information Today: Closing and Reopening: COVID-19’s Impact on Law Library Services House of Butter, June 5, 2020
Leading Law Departments
- The Covid-19 crisis: How does banking come back from this? Datasite (Merrill Corporation): Press Releases, June 5, 2020
- Gartner's COVID-19 Report: Focus on These 7 Cybersecurity Risk Areas Exterro Blog, June 5, 2020
- Data Preservation Challenges while Rebounding from COVID-19 Epiq Systems, June 4, 2020
- Building Bridges to Ensure Streamlined Legal Workflow during the COVID-19 Pandemic Corporate Legal Ops Consortium: Blog, June 4, 2020
- ALSP and Legal Tech Competition Won't Be 'Zero-Sum Game' Post-COVID-19 [Law.com] Casepoint: News, June 4, 2020
- A Post-Covid Warning To Compliance Officers Today's General Counsel: Career, June 4, 2020
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 | | Robert Morris, MD, PhD, Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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