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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
7,990,151 |
435,496 |
| US |
2,162,144 |
117,853 |
Research News
A Smart Phone App with 500,000 users demonstrates failure to quarantine The App found a substantial fraction of users left their homes on a daily basis across the US. Even after testing positive for SARS-COV-2, some users continued to go to work, some without a mask.
SARS-CoV-2 Infects 44% of Front Line Health Care Workers in London A prospective cohort study followed health care workers actively caring for COVID-19 patients at University College London Hospital for two months. 23% were positive for antibodies at the start of the study, and 21% tested positive for the virus, developed antibodies, or both. Of those who seroconverted, 58% were asymptomatic. It is notable that none of the patients initially positive for antibodies became reinfected.
A Meta-analysis suggests that the majority of transmission occurs before symptoms A simulation based on data from 17 published studies of SARS-CoV-2 transmission suggests that 56% of transmission occurs when cases are pre-symptomatic.
Analysis of Massive Medical Records Database Show COVID19 Symptoms An analysis of 77,000 records from patients tested for SARS-CoV-2 with 2,300 positive found those with lose of smell or test 27 more likely to test positive. Fever, cough, and respiratory difficulties gave 2.6, 2.2, and 2.2 times the rate of positive tests respectively. Muscle and joint pain as well as diarrhea were also elevated in positive tests.
The Prevalence of Viral Genes Influenced by Locations of Labs An analysis of gene sequences finds that some large, high-volume labs may influence the apparent prevalence of specific mutations and suggests a method to correct for this bias in the data.
High Resolution Electron Micrographs Produce Stunning Images of SARS CoV-2. Detailed images show binding to cell surface, formation of vacuoles, and contents of vacuoles.
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Unless otherwise noted, these pre-prints are not peer reviewed.
Covid19- Ahead of the Curve.
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Clinical Laboratory and Diagnostics
- One-Step Rapid Quantification of SARS-CoV-2 Virus Particles via Low-Cost Nanoplasmonic Sensors in Generic Microplate Reader and Point-of-Care Device bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- Rapid point of care nucleic acid testing for SARS-CoV-2 in hospitalised patients: a clinical trial and implementation study MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Evaluating the efficacy of RT-qPCR SARS-CoV-2 direct approaches in comparison to RNA extraction bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- The impact of viral transport media on PCR assay results for the detection of nucleic acid from SARS-CoV-2 and other viruses bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
Emergency Care and Triage
- Evaluation and Improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Infection Control
- Using surgical wrapping material for the fabrication of respirator masks MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Clinical Course and Outcomes
- Prevalence and mortality of Lung Comorbidities Among Patients with COVID-19: A systematic review and meta-analysis MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Association between Prolonged Intermittent Renal Replacement Therapy and All-Cause Mortality in COVID-19 Patients Undergoing Invasive Mechanical Ventilation: a Retrospective Cohort Study MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Theoretical Study of the Optical Spectra of SARS-CoV-2 Proteins ChemRxiv (Covid), June 11, 2020
Impact on Other Specialties
- COVID-19 infections and outcomes in patients with multiple myeloma in New York City: a cohort study from five academic centers MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Impact of COVID-19 pandemic on lung cancer treatment scheduling MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Reviews, Commentary, and Miscellaneous
- Quantitative PCR for cannabis flower containing SARs-CoV-2 bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- Unravelling the debate on heme effects in COVID-19 infections bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- Evaluation of Knowledge, Practices, Attitude and Anxiety of Pakistans Nurses towards COVID-19 during the Current Outbreak in Pakistan MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Mental Health
- Is the psychological well-being of a population associated with COVID-19 related survival? MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Trajectories of depressive symptoms among vulnerable groups in the UK during the COVID-19 pandemic MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Work-related and Personal Factors Associated with Mental Well-being during COVID-19 Response: A Survey of Health Care and Other Workers MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Drug Development
- Navigating Chemical Space By Interfacing Generative Artificial Intelligence and Molecular Docking bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- Improving Precision and Power in Randomized Trials for COVID-19 Treatments Using Covariate Adjustment, for Binary, Ordinal, and Time-to-Event Outcomes MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Designed peptides as potential fusion inhibitors against SARA-CoV-2 coronavirus infection bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
Newly Registered Clinical Trials
- Study of the Sars-Cov2 Neuroinvasiveness - COVID19 June 11, 2020
- Core Warming of COVID-19 Patients June 11, 2020
- Therapeutic Vaccine Trial of COVID-19 for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection June 11, 2020
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BASIC SCIENCE AND EPIDEMIOLOGY
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Virology, Immunology, and Pathophysiology
- The Distal Polybasic Cleavage Sites of SARS-CoV-2 Spike Protein Enhance Spike Protein-ACE2 Binding bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- SARS-CoV-2 sequence typing, evolution and signatures of selection using CoVa, a Python-based command-line utility bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- Comparative analysis of non structural protein 1 of SARS-COV2 with SARS-COV1 and MERS-COV: An in silico study bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
Vaccine Development
- Insight into vaccine development for Alpha-coronaviruses based on structural and immunological analyses of spike proteins bioRxiv: The Preprint Server for Biology (Covid), June 10, 2020
Epidemiology
- Rapid characterization of the propagation of COVID-19 in different countries MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- What does and does not correlate with COVID-19 death rates MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Knowledge, attitudes, and practices among the general population during COVID-19 outbreak in Iran: A national cross-sectional survey MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Modeling and Prediction
- Forecasting virus diffusion with simple Bayesian forecast combination bioRxiv: The Preprint Server for Biology (Covid), June 11, 2020
- COVID 19: Real-time Forecasts of Confirmed Cases, Active Cases, and Health Infrastructure Requirements for India and its States using the ARIMA model. MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Estimation of effects of contact tracing and mask adoption on COVID-19 transmission in San Francisco: a modeling study MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Public Health Intervention
- Testing for tracing or testing just for treating? A comparative analysis of strategies to face COVID-19 pandemic. MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Estimating effects of intervention measures on COVID-19 outbreak in Wuhan taking account of improving diagnostic capabilities using a modelling approach MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Reacting to outbreaks at neighboring localities MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Surveillance and sero-epidemiology
- A Novel Approach to Monitoring the COVID-19 Pandemic using Emergency Department Discharge Diagnoses MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Scalable and Resilient SARS-CoV-2 testing in an Academic Centre MedRxiv Server for Health Sciences: Coronavirus, June 10, 2020
- Identification of SARS-CoV-2 in wastewater in Japan by multiple molecular assays-implication for wastewater-based epidemiology (WBE) MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
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Coronavirus Research Resources
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Iran
- Knowledge, attitudes, and practices among the general population during COVID-19 outbreak in Iran: A national cross-sectional survey MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Italy
- Survival of hospitalized COVID-19 patients in Northern Italy: a population-based cohort study by the ITA-COVID19 Network MedRxiv Server for Health Sciences: Coronavirus, June 10, 2020
France
- Bayesian investigation of SARS-CoV-2-related mortality in France MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
United Kingdom
- Ethnicity, comorbidity, socioeconomic status, and their associations with COVID-19 infection in England: a cohort analysis of UK Biobank data MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
Other International News
- COVID 19: Real-time Forecasts of Confirmed Cases, Active Cases, and Health Infrastructure Requirements for India and its States using the ARIMA model. MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Evaluation of Knowledge, Practices, Attitude and Anxiety of Pakistans Nurses towards COVID-19 during the Current Outbreak in Pakistan MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Identification of SARS-CoV-2 in wastewater in Japan by multiple molecular assays-implication for wastewater-based epidemiology (WBE) MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
- Assessment of Experiences of Preventive Measures Practice including Vaccination History and Health Education among Umrah Pilgrims in Saudi Arabia, 1440H-2019 MedRxiv Server for Health Sciences: Coronavirus, June 11, 2020
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Business and Economic News
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Business News
- PS5 Games Revealed (Trailers): Every Game Sony Just Announced Wired.com, June 11, 2020
- Twitter's Newest Trick Relies on Tracking More of Your Clicks Wired.com, June 11, 2020
- This Is What the PlayStation 5 Looks Like. Both of Them Wired.com, June 11, 2020
Economics Blogs
- The Public Finance Implications of COVID-19 Macro and Other Market Musings, June 11, 2020
- Guest Contribution: “How the Coronavirus Crisis is Affecting Japanese and American Businesses: Evidence from the Stock Market” EconBrowser, June 11, 2020
- Higher Debt, Deeper Digitization, and Less Globalization Will be Coronavirus Legacies Economonitor, June 11, 2020
Top Economics News
- Eurogroup : Greek economy to be hit hardest in EU due to COVID-19 pandemic - Economics - 11/06/2020 - Kuwait News Agency (Euro Economies), June 11, 2020
- Covid-19 crisis should herald change in Greece's productivity model, Delphi forum told | Kathimerini - www.ekathimerini.com (Euro Economies), June 11, 2020
- CGTN: Super Virus – COVID-19: How We Got Here - Argus Press (Euro Economies), June 11, 2020
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Law Technology
- “How long will I need to be in here?”: The “Elder Statesman” dies after contracting COVID-19 in NY prison - Yale Daily News (Law Library), June 11, 2020
- What Were My Struggles During COVID-19 and What Are My Solutions to Implement Moving Forward ILTA Blogs, June 11, 2020
- How COVID-19 is Changing our Relationship with Data Data Science Central: Featured Blog Posts, June 11, 2020
Legal Administrator
- Latest ACC Flash Poll Examines Impact of COVID-19 on Wellbeing and Mental Health of Over 450 In-House Lawyers ACC News, June 11, 2020
- London High Court claims bounce back in May after Covid-19 slump Global Legal Post: Big Stories, June 11, 2020
- What Will Law Departments Look Like After COVID-19? Inside Counsel, June 11, 2020
Librarian News
- Article: Lessons for young sole practitioners from COVID-19 House of Butter, June 11, 2020
- Trump trashes 50-year-old environmental law, blames coronavirus beSpacific, June 11, 2020
- Coronavirus Could Make America’s Gun Problem Even Deadlier beSpacific, June 11, 2020
Leading Law Departments
- What Will Law Departments Look Like After COVID-19? Inside Counsel, June 11, 2020
- Subscription-Based Businesses Under Attack in COVID-19 Pandemic Inside Counsel, June 10, 2020
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 | | Robert Morris, MD, PhD, Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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