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COVID-19 Report
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 The Count
| Region |
Cases |
Deaths |
| World |
11,632,961 |
538,217 |
| US |
3,001,452 |
132,675 |
Is Trump Killing Americans? Evidence suggests that Donald Trump is directly and objectively responsible for the deaths of tens of thousands of Americans and the severe illness and chronic disability of hundreds of thousands more. Epidemiologists seek to identify risk factors for disease. It is time to evaluate our Risk Factor in Chief.
Research News
French study suggests that young children unlikely to transmit SARS-CoV-2 A study of three French elementary schools with students who had documented infections found no secondary cases among pupils, teachers, and staff during the 14 days following their diagnosis. The three students had mild symptoms.
Non-medical staff at higher risk of SARS-CoV-2 infections than ICU caregivers A study of Oxford University Hospitals found that working in hospital units interacting with COVID-19 patients result in a 2.5 fold increase in infection risk. Porters and cleaners had a doubling of risk, but having an infected household contact caused a 4.6-fold increase. ICU staff actually had half the risk of comparable workers in other areas of the hospitals.
Italian data demonstrate impact of mask mandates A study of Italian data from six cities clearly demonstrates that public mandates to wear mask increased the rate of decline in COVID-19 cases beyond the benefits of lockdown policies. A US study demonstrated a similar positive effect from masking mandates.
Use of multiple SARS-CoV-2 antigens improves value of antibody screening tests A French study using seven different SARS-CoV-2 antigens along with two seasonal coronavirus antigens and three flu antigens for comparison provides a uniquely sensitive test for evaluating past infections and mild infections.
Study documents the rise of SARS-CoV-2 infections in New York A study of residual samples from patients at Mt. Sinai hospital shows that there were cases in the city by early to mid February and the infection rate in the city rose to 19% by mid-April. This appears to validate the early seroprevalence studies by the state health department.
SARS-CoV-2 killed 1.5% of those infected in New York City A team from Columbia University and the New York City Health Department estimates that the overall infection fatality rate during the spring peak was 1.45% with age specific rates as high as 17% for those 75 and over.
Evidence suggests that some people without antibodies to SARS-CoV-2 may have been exposed A study of family members of COVID-19 cases found evidence of T-cell immunity even among subjects without SARS-CoV-2 antibodies. This suggests both that the infection may be even more widespread than suggested by antibody screening and that there may be some immunity among those without antibodies.
Only half of people wearing masks do so correctly A Brazilian study in an area with high incidence of COVID-19 found that 85% of the population wore masks, but 47% of those wearing masks either wore them incorrectly, had a poorly fitting mask, or was observed touching their face.
Fourteen day quarantine may not be long enough Researchers from Spain and the University of Texas estimated that up to 9.2% of patients 42 or younger and 18.6% of patients older than 42 years could develop symptoms after the end of the period.
A quarter of samples from hospital HVAC system positive for SARS-CoV-2 25% of samples from the air handling system of the Oregon Health Sciences hospital were positive for the virus. The samples were not evaluated for viability.
Exposure to Seasonal Coronaviruses does not appear to influence severity of SARS-CoV-2 infections A team of French researchers found no significant difference in levels of antibodies to seasonal (non-SARS-CoV-2) coronavirus antibody levels among three groups, COVID-19 patients, children with multi system inflammatory (Kawasaki) syndrome related to SARS-CoV-2, and a group of mildly symptomatic or asymptomatic controls. This suggests that the reduced severity of COVID-19 in young children cannot be explained by exposure to prior exposure to other types of corona viruses.
French study shows five fold increase in Kawasaki Syndrome during COVID-19 peak* Researchers at a tertiary care pediatric hospital in Paris found a dramatic spike in Kawasaki syndrome, a severe, potentially fatal, multi-system inflammatory disease, in response to SARS-CoV-2 and retrospectively document a smaller but significant spike in response to the 2009, H1N1 pandemic.
SARS-CoV-2 does not appear to spread among hospitalized patients* A Dutch study of viral genetics among patients and staff in three hospitals does not find evidence of a specific genotype spreading within the hospital, suggesting nosocomial spread is not a prominent concern
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* indicates a published article. Otherwise these are pre-prints (not peer reviewed).
Recent Posts Covid19- Ahead of the Curve.
The Epidemiology of Politics Packing thousands of people together in an arena (or even a church) in a city where COVID-19 cases are spiking to yell, chant, and cheer for a couple of hours with no masks on might seem like a bad idea. A really, really bad idea..
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Clinical Laboratory and Diagnostics
- Nanotrap® particles improve detection of SARS-CoV-2 for pooled sample methods, extraction-free saliva methods, and extraction-free medium methods bioRxiv: The Preprint Server for Biology (Covid), June 30, 2020
- A Streamlined CyTOF Workflow To Facilitate Standardized Multi-Site Immune Profiling of COVID-19 Patients MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- AIDCOV: An Interpretable Artificial Intelligence Model for Detection of COVID-19 from Chest Radiography Images MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Emergency Care and Triage
- Swarm Learning as a privacy-preserving machine learning approach for disease classification bioRxiv: The Preprint Server for Biology (Covid), June 30, 2020
- Protocol for the development and evaluation of a tool for predicting risk of short-term adverse outcomes due to COVID-19 in the general UK population MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Blood parameters measured on admission as predictors of outcome for COVID-19; a prospective UK cohort study MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Infection Control
- Presence of Live SARS-CoV-2 Virus in Feces of Coronavirus Disease 2019 (COVID-19) Patients: A Rapid Review MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Silk fabric as a protective barrier for personal protective equipment and as a functional material for face coverings during the COVID-19 pandemic MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Indoor Exposure to Commonly Used Disinfectants During the COVID-19 Pandemic ChemRxiv (Covid), June 29, 2020
Clinical Case Management
- Extracorporeal Cytokine Hemadsorption in Severe COVID-19 Respiratory Failure MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Electrocardiographic safety of daily Hydroxychloroquine 400mg plus Azithromycin 250mg as an ambulatory treatment for COVID-19 patients in Cameroon. MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Effects of Anticoagulants and Corticosteroids therapy in patients affected by severe COVID-19 Pneumonia MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Acute peritoneal dialysis in the treatment of COVID-19-related acute kidney injury Oxford Academic Journals: Coronavirus, June 30, 2020
- Accelerated hyaluronan concentration as the primary driver of morbidity and mortality in high-risk COVID-19 patients: with therapeutic introduction of an oral hyaluronan inhibitor in the prevention of Induced Hyaluronan Storm Syndrome MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
- Short-Term Corticosteroids in SARS-CoV2 Patients: Hospitalists' Perspective MedRxiv Server for Health Sciences: Coronavirus, June 27, 2020
ICU Care
- Secondary pneumonia in critically ill ventilated patients with COVID-19 MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
- Secondary pneumonia in critically ill ventilated patients with COVID-19 MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
Clinical Course and Outcomes
- A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Association of BMI and Obesity with Composite poor outcome in COVID-19 adult patients: A Systematic Review and Meta-Analysis MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Higher clinical acuity and 7-day hospital mortality in non-COVID-19 acute medical admissions: prospective observational study. MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Impact on Other Specialties
- Impact of the Novel Coronavirus Disease (COVID-19) on Treatment Adherence and Sleep Duration in Obstructive Sleep Apnea Patients Treated with Positive Airway Pressure MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Cancer inpatient with COVID-19: a report from the Brazilian National Cancer Institute MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- THE EXPERIENCE OF UK BLADDER CANCER PATIENTS DURING THE COVID-19 PANDEMIC: A SURVEY-BASED SNAPSHOT MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Reviews, Commentary, and Miscellaneous
- Readability of selected governmental and popular health organization websites on Covid-19 public health information: A descriptive analysis MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Mapping the Global Research and Clinical Trials in COVID-19 MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Mental Health
- SARS-CoV-2 & Pediatric Mental Health: A Review of Recent Evidence MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- The psychological impact of COVID-19 on the mental health in the general population Oxford Academic Journals: Coronavirus, June 30, 2020
- Problem drinking before and during the COVID-19 crisis in US and UK adults: Evidence from two population-based longitudinal studies MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
- The impact of SARS-CoV-2 transmission fear and COVID-19 pandemic on the mental health of patients with primary immunodeficiency disorders, severe asthma, and other high-risk groups MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
- Social media and smartphone app use predicts maintenance of physical activity during Covid-19 enforced isolation in psychiatric outpatients MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
Drug Development
- The Potential role of Procyanidin as a Therapeutic Agent against SARS-CoV-2: A Text Mining, Molecular Docking and Molecular Dynamics Simulation Approach ChemRxiv (Covid), June 30, 2020
- Artificial Intelligence Guided De Novo Molecular Design Targeting COVID-19 ChemRxiv (Covid), June 30, 2020
- Early Hemoglobin kinetics in response to ribavirin: Safety lesson learned from Hepatitis C to CoVID-19 therapy MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Newly Registered Clinical Trials
- Povidone-Iodine Rinses in the Management of COVID-19 June 29, 2020
- Vitamin D Supplementation in Patients With COVID-19 June 29, 2020
- Efficacy and Safety Study of BDB-001 in Severe COVID-19 With ALI/ARDS June 29, 2020
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BASIC SCIENCE AND EPIDEMIOLOGY
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Virology, Immunology, and Pathophysiology
- Using nucleocapsid proteins to investigate the relationship between SARS-CoV-2 and closely related bat and pangolin coronaviruses bioRxiv: The Preprint Server for Biology (Covid), June 30, 2020
- Stereotypic Neutralizing VH Clonotypes Against SARS-CoV-2 RBD in COVID-19 Patients and the Healthy Population bioRxiv: The Preprint Server for Biology (Covid), June 29, 2020
- SARS-CoV-2 Spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity bioRxiv: The Preprint Server for Biology (Covid), June 29, 2020
Vaccine Development
- Modified Vaccinia Ankara Based SARS-CoV-2 Vaccine Expressing Full-Length Spike Induces Strong Neutralizing Antibody Response bioRxiv: The Preprint Server for Biology (Covid), June 28, 2020
Epidemiology
- Statistics associated with the lethality of COVID-19 by age group and gender in Mexico MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- COVID-19 related mortality and spread of disease in long-term care: a living systematic review of emerging evidence MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Superspreading in Early Transmissions of COVID-19 in Indonesia MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Modeling and Prediction
- Predictive model of COVID-19 incidence and socioeconomic description of municipalities in Brazil MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- A new estimation method for COVID-19 time-varying reproduction number using active cases MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- The Influence of Time-Limited Immunity on a COVID-19 Epidemic: A Simulation Study MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Public Health Intervention
- Knowledge and Behaviors Related to the COVID-19 pandemic in Malawi MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Evaluation of national responses to COVID-19 pandemic based on Pareto optimality MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- From predictions to prescriptions: A data-driven response to COVID-19 MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Assessing the nationwide impact of COVID-19 mitigation policies on the transmission rate of SARS-CoV-2 in Brazil MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
- Cost Benefit Analysis of Limited Reopening Relative to a Herd Immunity Strategy or Shelter in Place for SARS-CoV-2 in the United States MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
- Face mask wearing rate predicts country's COVID-19 death rates MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
Surveillance and sero-epidemiology
- Testing for tracing or testing just for treating? A comparative analysis of strategies to face COVID-19 pandemic. MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Time is of the essence: impact of delays on effectiveness of contact tracing for COVID-19, a modelling study MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- COVID-19: Saving lives and livelihoods using population density driven testing MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Preprints
- A Predictive Model of the Temperature-Dependent Inactivation of Coronaviruses ChemRxiv (Covid), July 3, 2020
- Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and correlation to tissue damage bioRxiv: The Preprint Server for Biology (Covid), July 2, 2020
- Unsupervised cluster analysis of SARS-CoV-2 genomes indicates that recent (June 2020) cases in Beijing are from a genetic subgroup that consists of mostly European and South(east) Asian samples, of which the latter are the most recent bioRxiv: The Preprint Server for Biology (Covid), July 2, 2020
Published Literature
- Rapid development and deployment of high‐volume vaccines for pandemic response Wiley: Coronavirus Research & News, June 30, 2020
- Adapting protocols for the care of surgical patients during the COVID‐19 pandemic Wiley: Coronavirus Research & News, June 30, 2020
- Conferences After COVID and Academics in Adversity: Physical Globalization is Fragile, But so Too is Internet Neutrality Wiley: Coronavirus Research & News, June 30, 2020
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Coronavirus Research Resources
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China
- Epidemiological characteristics of the first 100 cases of coronavirus disease 2019 (COVID-19) in Hong Kong Special Administrative Region, China, a city with a stringent containment policy Oxford Academic Journals: Coronavirus, June 30, 2020
- Pandemic Causes China To Ban Breeding Of Bamboo Rats And Other Wild Animals NPR: Health, June 28, 2020
- Data-driven analysis on the simulations of the spread of COVID-19 under different interventions of China MedRxiv Server for Health Sciences: Coronavirus, July 1, 2020
- Cluster analysis of epidemiological characteristic features of confirmed cases with the novel coronavirus (COVID-19) outside China: a descriptive study MedRxiv Server for Health Sciences: Coronavirus, July 1, 2020
- Beijing approves experimental Covid-19 vaccine for use in Chinese military CNN.com - Health, June 30, 2020
- Citywide Nucleic Acid Screening of SARS-CoV-2 Infections in Post-lockdown Wuhan, China: Results and Implications MedRxiv Server for Health Sciences: Coronavirus, June 30, 2020
South Korea
- Distinctive trajectories of COVID-19 epidemic by age and gender: a retrospective modeling of the epidemic in South Korea MedRxiv Server for Health Sciences: Coronavirus, June 27, 2020
- South Korea Holds Onto Patient Data From Prior Coronavirus, Worrying Privacy Groups NPR: Health, June 30, 2020
Italy
- Data-driven estimation of change points reveal correlation between face mask use and accelerated curtailing of the COVID-19 epidemic in Italy MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
Spain
- Beta regression with spatio-temporal effects as a tool for hospital impact analysis of initial phase epidemics: the case of COVID-19 in Spain MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Retrospective Methodology to Estimate Daily Infections from Deaths (REMEDID) in COVID-19: the Spain case study MedRxiv Server for Health Sciences: Coronavirus, June 28, 2020
- Lockdown measures and relative changes in the age-specific incidence of SARS-CoV-2 in Spain MedRxiv Server for Health Sciences: Coronavirus, July 2, 2020
Germany
- Face Masks Considerably Reduce Covid-19 Cases in Germany MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Associations of exercise and social support with mental health during quarantine and social-distancing measures during the COVID-19 pandemic: A cross-sectional survey in Germany MedRxiv Server for Health Sciences: Coronavirus, July 2, 2020
France
- SARS-CoV-2 infection in primary schools in northern France: A retrospective cohort study in an area of high transmission MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Bayesian investigation of SARS-CoV-2-related mortality in France MedRxiv Server for Health Sciences: Coronavirus, July 2, 2020
- Modelling lockdown-induced secondary COVID waves in France MedRxiv Server for Health Sciences: Coronavirus, July 1, 2020
- Modelling lockdown-induced secondary COVID waves in France MedRxiv Server for Health Sciences: Coronavirus, June 30, 2020
- Estimating the state of the Covid-19 epidemic in France using a non-Markovian model MedRxiv Server for Health Sciences: Coronavirus, June 30, 2020
United Kingdom
- Clinical trials (and tribulations): the immediate effects of COVID-19 on IBD clinical research activity in the United Kingdom Oxford Academic Journals: Coronavirus, June 29, 2020
- Transmission Dynamics of the COVID-19 Epidemics in England MedRxiv Server for Health Sciences: Coronavirus, July 2, 2020
- Social contact and inequalities in depression and loneliness among older adults: A mediation analysis of the English Longitudinal Study of Ageing MedRxiv Server for Health Sciences: Coronavirus, July 2, 2020
- A geotemporal survey of hospital bed saturation across England during the first wave of the COVID-19 Pandemic MedRxiv Server for Health Sciences: Coronavirus, July 1, 2020
- Excess mortality in England and Wales during the first wave of the COVID-19 pandemic MedRxiv Server for Health Sciences: Coronavirus, June 30, 2020
- COVID-19, smoking, vaping and quitting: A representative population survey in England MedRxiv Server for Health Sciences: Coronavirus, June 30, 2020
Other International News
- People with coronavirus are crossing the US-Mexico border for medical care CNN.com - Health, June 30, 2020
- Statistics associated with the lethality of COVID-19 by age group and gender in Mexico MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
- Superspreading in Early Transmissions of COVID-19 in Indonesia MedRxiv Server for Health Sciences: Coronavirus, June 29, 2020
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Business and Economic News
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Business News
- Some US states return to previous restrictions to slow surge of coronavirus cases CNN.com - Health, June 30, 2020
- More than 500,000 people have been killed by Covid-19. A quarter of them are Americans CNN.com - Health, June 30, 2020
- Here's how much Covid-19 drug remdesivir will cost CNN.com - Health, June 30, 2020
Economics Blogs
- Eight priorities to strengthen international cooperation against Covid-19 VoxEU.org, June 30, 2020
- How non-standard workers are affected and protected during the Covid-19 crisis VoxEU.org, June 30, 2020
- COVID-19 has increased and broadened inequality in psychological distress in the UK VoxEU.org, June 30, 2020
Top Economics News
- Brazil's Economy Entered Recession in 1Q as Coronavirus Shut Many Businesses - Marketscreener.com (Brazilian Economy), June 30, 2020
- Revenue’s wage subsidy checks, Brexit stalemate, and Covid-19 scams - The Irish Times (Brexit Economy News), June 30, 2020
- Brazil reports over 30,000 new COVID-19 cases as total rises over 1.34 million - UNTV News - UNTV News (Brazilian Economy), June 30, 2020
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Law Technology
- How E-Discovery Software Is Helping Battle COVID-19 Above the Law - Legal Technology (eDiscovery), June 29, 2020
- The COVID-19 Recovery Playbook: What Law Firms Learned During Quarantine And How They’re Embracing A Digital Transformation [Sponsored] Above the Law - Legal Technology, June 29, 2020
- AI's Big Moment: A Full Battalion in the COVID Infantry Law Technology News, June 29, 2020
Legal Administrator
- Why HR Needs a Global Mind-Set Post-COVID EntertainHR, June 30, 2020
- ICYMI: U.S. Department of Labor Acts to Help American Workers and Employers During the Coronavirus Pandemic OSHA News Releases, June 29, 2020
- CA's San Quentin - More than 1/3rd of Inmates Have Coronavirus Law and More, June 29, 2020
Librarian News
- COVID-19 NEWS: 'How COVID-19 Has Changed Americans' Comfort Levels, Behaviors and Outlooks' Information Today: News Breaks, June 30, 2020
- 5 things you should do right now to fight the rising number of COVID-19 cases beSpacific, June 30, 2020
- How E-Discovery Software Is Helping Battle COVID-19 Above the Law, June 29, 2020
Leading Law Departments
- The COVID-19 Recovery Playbook: What Law Firms Learned During Quarantine And How They’re Embracing A Digital Transformation Joe Borstein - Pangea3 - Blog, July 1, 2020
- Infographic | Survey Results: How Has Coronavirus Impacted Legal Ops? Mitratech: Press Releases, June 30, 2020
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 | | Robert Morris, MD, PhD, Editor
Dr. Robert Morris is an epidemiologist and award-winning author who has taught epidemiology at Tufts and Harvard and has advised the CDC, the EPA, NIH, and the President's Cancer Panel. |
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